Index Catalog // ScholarsArchive@OSU

A Bayesian Treatise on the Replication Crisis in Science

Creator:: Gibson, True E.
Abstract:: Over the past decade, it has come to light that many published scientific findings cannot be reproduced. This has led to the replication crisis in science. Many researchers feel that they can no longer trust much of what they read in scientific journals, and the public is becoming ever more...
Resource Type:: Honors College Thesis
Full Text:: . Abstract approved: __________________________________________________ Jonathan Kaplan Abstract

The conversion of some monoalkylhydrazines to their corresponding hydrocarbons by a hepatic microsomal enzyme system in rat

Creator:: Prough, Russell A.
Abstract:: An aspect of the metabolism of monoalkylhydrazines has been investigated using both intact rats and rat liver microsomal enzyme preparations. Intact rats respired propane and n-butane on administration of 0.3-0.5 mmoles of isopropyl- and n-butylhydrazine, respectively. Based upon dose administered, a five to ten percent yield of hydrocarbon was obtained....
Resource Type:: Dissertation
Full Text:: b 5 and P450 did not appear to play a role in the reaction. The lack of correlation between loss

The β-glucosidase system of the thermophilic fungus Chaetomium thermophile

Creator:: Lusis, Aldons Jekabs
Abstract:: The thermophilic fungus Chaetomium thermophile was shown to contain three major β-glucosidases, a cell-bound cellobiase, a cellbound aryl-β-glucosidase and an extracellular aryl-β-glucosidase. The enzymes were partially purified and studied with respect to thermal stability and certain kinetic parameters. Two of the β-glucosidases are fairly stable at the maximum growth temperature...
Resource Type:: Dissertation
Full Text:: and an extracellular aryl-B-glucosidase. The enzymes were partially purified and studied with respect

Glutamate dehydrogenase : I.Flourescence polarization studies of the self-association. II.Flourescence and circular dichroism studies of the heterotropic interactions

Creator:: Malencik, Dean Anthony
Abstract:: Fluorescence polarization measurements on beef liver glutamate dehydrogenase conjugated with pyrene butyric acid demonstrate that the association of the enzyme is adequately described by a reversible indefinite association with a single equilibrium constant. The data obtained with protein concentrations up to 0.7 mg/ml in 0.05 M potassium phosphate, pH 7....
Resource Type:: Dissertation
Full Text:: extent (Sedgwick and Frieden, 1968; Corman, Prescott and Kaplan, 1967). 3. The purine nucleotides, in

Production of peptide growth factors by oncogene-transformed balb serum-free mouse embryo cells

Creator:: Chang, Yung-jin
Abstract:: DNA from the human squamous carcinoma cell line, SK-MES-1, and the plasmids, pUC EJ6.6 containing H-ras oncogene, pSVc-mycl containing cellular myc gene, pNRSac containing N-ras oncogene, pBR SV containing SV40 virus DNA, pSV2-neu containing neu oncogene and pSV2-neo containing neomycin resistant gene were used to transform Balb serum-free derived mouse...
Resource Type:: Masters Thesis
Full Text:: -1037. 4. Kaplan, P. L., Anderson, M. and Ozanne, B. (1982). "Transforming growth factor production

The purification and characterization of a ribonuclease from bovine aorta

Creator:: Lewis, Roger Allen
Abstract:: Reports of investigations on nucleases in arterial tissue are few in number. The present study is concerned with the purification and characterization of an aortic ribonuclease. An endonuclease (ARNase I) isolated from the bovine aorta has been purified 4611 fold by means of fractionation with ethanol, acid extraction, isoionic precipitation,...
Resource Type:: Dissertation
Full Text:: A and B, from UpC- ARNase hydrolysis. 19. Co-chromatography of UpC -ARNase I hydrolysis products

Reactions of horseradish peroxidase with the isothiocyanates of horseradish oil

Creator:: Darussamin, Asril
Abstract:: Horseradish peroxidase (HRP) has been investigated extensively and for many years. In spite of this it still exhibits unexplained anomalies. Among these is variation in the reported number of isozymes (from 7 to 42), and reports of instability of the isozyme patterns. Since horseradish is a rich source of organic...
Resource Type:: Dissertation
Full Text:: elution profile of Fraction (B + C) 46 3. Isoelectric focusing of HRP and HRP CM-cellu- lose column

Purification and characterization of an alkaline phosphatase from Halobacterium salinarium

Creator:: McParland, Reginald Harry
Abstract:: The halophilic alkaline phosphatase of Halobacterium salinarium has been purified to a specific activity of 3,000-3,200 units per mg of protein. The purification scheme consisted of acetone and ammonium sulfate fractionations, and molecular sieving and adsorption chromatography on Sephadex G -50. The enzyme was stabilized during purification by the presence...
Resource Type:: Dissertation

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

Creator:: Wang, Jun-Lan
Abstract:: Low concentrations of hexachlorophene (HCP) inhibit a number of pyridine nucleotide-linked dehydrogenase enzymes. The I₅₀ HCP concentrations were 105 μM for pig heart isocitrate dehydrogenase (ICD), 65 μM for horse liver alcohol dehydrogenase, 39 μM for torula yeast glucose-6-phosphate dehydrogenase (G6PD), 6.0 μM for beef heart malate dehydrogenase, and 1.6...
Resource Type:: Dissertation
Full Text:: inhibition 79 Part B: Studies on the Mechanism of Inhibition of G6PD by HCP 81 Density gradient

Hydrogen-stimulated CO₂ fixation and coordinate derepression of hydrogenase and ribulosebisphosphate carboxylase in a H₂-uptake positive strain of Rhizobium japonicum

Creator:: Simpson, Frank Berry
Abstract:: H₂-uptake positive strains (122 DES and SR) and H₂-uptake negative strains SR2 and SR3 of Rhizobium japonicum were examined for ribulosebisphosphate (RuBP) carboxylase and H₂-uptake activities during growth conditions which induced formation of the hydrogenase system. The rate of ¹⁴CO₂ uptake by hydrogenase-induced cells was about six times greater in...
Resource Type:: Masters Thesis
Full Text:: . S-methylmalonyl CoAf_JL:_2R-methylmalonyl CoA 3 0 3. 00C-CH-C-SCoA B 12 enzyme 500C-CH2-CH2-C

ScholarsArchive@OSU

A Bayesian Treatise on the Replication Crisis in Science

The conversion of some monoalkylhydrazines to their corresponding hydrocarbons by a hepatic microsomal enzyme system in rat

The β-glucosidase system of the thermophilic fungus Chaetomium thermophile

Glutamate dehydrogenase : I.Flourescence polarization studies of the self-association. II.Flourescence and circular dichroism studies of the heterotropic interactions

Production of peptide growth factors by oncogene-transformed balb serum-free mouse embryo cells

The purification and characterization of a ribonuclease from bovine aorta

Reactions of horseradish peroxidase with the isothiocyanates of horseradish oil

Purification and characterization of an alkaline phosphatase from Halobacterium salinarium

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

Hydrogen-stimulated CO₂ fixation and coordinate derepression of hydrogenase and ribulosebisphosphate carboxylase in a H₂-uptake positive strain of Rhizobium japonicum

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