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Filtering by: Creator Kaplan, Jared Remove constraint Creator: Kaplan, Jared Degree Field Biochemistry and Biophysics Remove constraint Degree Field: Biochemistry and Biophysics

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  • Oxidative stress in amyotrophic lateral sclerosis : the role of cellular senescence and glutathione

    Creator:
    Beilby, Pamela R.
    Abstract:
    Amyotrophic lateral sclerosis (ALS) is a devastating neurological disorder characterized by neuromuscular junction decay, motor neuron death, progressive paralysis, and eventually death of the individual, usually by respiratory failure. Oxidative stress is a prominent hallmark of the disease and is often accompanied and exacerbated by mitochondrial dysfunction and neuroinflammation. This...
    Resource Type:
    Dissertation
    Full Text:
    my family. You have borne the brunt of my agonies in this process. Thank you, Jared and Bianca, for