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The in vivo metabolism of ethyl-N, N,-di-n-propylthiolcarbamate in rats

Creator:: Ong, Visitacion Yu
Abstract:: The metabolism of ¹⁴C-labeled ethyl -N, N-di-n- propylthiolcarbamate (EPTC- ¹⁴C) was studied in adult female rats. Single oral doses of EPTC-¹⁴C ranging from 0. 6 to 100. 6 mg were given and the elimination pattern of ¹⁴C was determined. Results of 18 experiments showed that increasing the doses of EPTC-...
Resource Type:: Masters Thesis
Full Text:: Privacy S. C. Fang The metabolism of 14C-labeled ethyl -N, N-di-n- propylthiol- carbamate (EPTC- 14C

In vivo and in vitro metabolism of 4-benzo(b)thienyl-N-methylcarbamate and 4-hydroxy benzothiophene by the white rat

Creator:: Miaullis, John Bartley
Abstract:: In vitro studies of Mobam (4-benzo(b)thienyl N-methylcarbamate) metabolism have demonstrated that at least three ether soluble metabolites are formed in a microsomal system fortified with reduced triphosphopyridine nucleotide (NADPH). One of the metabolites was identical to 4HBT (4-hydroxy benzothiophene), the phenol of Mobam. The other two metabolites did not possess...
Resource Type:: Masters Thesis
Full Text:: MIAULLIS for the M. S. (Name of student) (Degree) in Biochemistry presented on March 27, 1968 (Major

In vivo and in vitro metabolism of 4-benzo(b)thienyl-N-methylcarbamate and 4-hydroxy benzothiophene by the white rat

Creator:: Miaullis, John Bartley
Abstract:: In vitro studies of Mobam (4-benzo(b)thienyl N-methylcarbamate) metabolism have demonstrated that at least three ether soluble metabolites are formed in a microsomal system fortified with reduced triphosphopyridine nucleotide (NADPH). One of the metabolites was identical to 4HBT (4-hydroxy benzothiophene), the phenol of Mobam. The other two metabolites did not possess...
Resource Type:: Masters Thesis
Full Text:: MIAULLIS for the M. S. (Name of student) (Degree) in Biochemistry presented on March 27, 1968 (Major

Studies on the inhibition of bovine plasma amine oxidase by hydrazines

Creator:: Hucko-Haas, Jacqueline Elizabeth
Abstract:: Several aspects of the potent inhibition of bovine plasma amine oxidase (PAO) by hydrazines were investigated by kinetic and preparative means. The inhibition was classified as pseudo-irreversible by the method of Ackerman and Potter (Proc. Soc. Exptl. Biol. Med. 72, 1 (1949), and was found to exhibit Zone B kinetic...
Resource Type:: Dissertation
Full Text:: : Studies on the Inhibition of Bovine Plasma Amine Oxidase by Hydrazine s Abstract approved: Redacted for

An Accumulation of Senescent Cells May Contribute to Chronic Inflammation of the Mammalian Liver

Creator:: Sugiyama, Aaron
Abstract:: The aging process is a biological phenomenon in mammals that heavily contributes to the onset of chronic diseases. While there are many theories that attempt to explain the biological onset of aging, one emerging theory involves chronic inflammation. Chronic inflammation has been previously linked to several age-related diseases and is...
Resource Type:: Honors College Thesis
Full Text:: Natl Acad Sci U S A 92, 9363–9367 (1995). 9. Doxaki, C., Kampranis, S. C., Eliopoulos, A. G

Mitochondrial glutathione and the effect of perturbed calcium homeostasis on rat hepatocyte thiols

Creator:: Olafsdottir, Kristin
Abstract:: Recent studies have demonstrated that perturbations of intracellular thiol and calcium homeostasis may be important events in the early development of cell injury by toxic chemicals. Incubation of isolated rat hepatocytes in a calcium free medium, severely depleted intracellular Ca²⁺ levels and resulted in the loss of both cytosolic and...
Resource Type:: Dissertation
Full Text:: :13ructed 177/4l Ctt cla .'Z'S FICA scin resus=enaect iA It`er w=s. C11Z3Cli 011 1 fmrt 13CCC

Changes in enzyme activities of the isoprenoid pathway in germinating Pisum sativum

Creator:: Green, Terrence Robert, 1944-
Abstract:: The nature of the isoprenoid pathway and diversity of biologically significant products suggests that the pathway may be highly regulated, particularly under stress conditions, where the availability of high energy intermediates is limited. It was postulated that germinating seeds suffer from a limited supply of available energy and must therefore...
Resource Type:: Dissertation
Full Text:: Isoprenoid Intermediate s 37 Assay of Water Imbibition During Germination 38 Protein Determinations 39

Biophysical basis of macromolecular assembly in the dynein cargo attachment complex

Creator:: Hall, Justin Daniel
Abstract:: Cytoplasmic dynein is an ATP-dependent, microtubule-based molecular motor involved in the positioning and trafficking of cellular cargo. The cargo binding sub-domain of dynein contains the natively disordered intermediate chain (IC) and the homodimeric light chains (Tctex1, LC8 and LC7). The structure and stoichiometry of this complex, how the light chains...
Resource Type:: Dissertation
Full Text:: are: Yeast 2-hybrid (Y2H), coimmunoprecipitation (CoImm) and glutathione S-transferase-pull down (GST

Effect of hemi-methylated CG dinucleotide on Z-DNA stability : crystallographic and solution studies

Creator:: Bononi, Judy
Resource Type:: Masters Thesis
Full Text:: B- to Z-DNA transition free energies (AGT(s-z)) 40 5. Flow chart of constrained refinement

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation

ScholarsArchive@OSU

The in vivo metabolism of ethyl-N, N,-di-n-propylthiolcarbamate in rats

In vivo and in vitro metabolism of 4-benzo(b)thienyl-N-methylcarbamate and 4-hydroxy benzothiophene by the white rat

In vivo and in vitro metabolism of 4-benzo(b)thienyl-N-methylcarbamate and 4-hydroxy benzothiophene by the white rat

Studies on the inhibition of bovine plasma amine oxidase by hydrazines

An Accumulation of Senescent Cells May Contribute to Chronic Inflammation of the Mammalian Liver

Mitochondrial glutathione and the effect of perturbed calcium homeostasis on rat hepatocyte thiols

Changes in enzyme activities of the isoprenoid pathway in germinating Pisum sativum

Biophysical basis of macromolecular assembly in the dynein cargo attachment complex

Effect of hemi-methylated CG dinucleotide on Z-DNA stability : crystallographic and solution studies

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

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