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Filtering by: Creator Machovina, Melodie M. Degree Field Biochemistry and Biophysics

In vivo Reactions of Tetrazines Incorporated through Genetic Code Expansion

Creator:

Blizzard, Robert J.

Abstract:

The inverse electron demand Diels Alder reaction between tetrazines and strained alkenes is an exceptionally useful tool in functionalizing to biomolecules since it is orthogonal to the chemistry of most living systems and have exceptionally high rate constants. In particular reactions between strained trans-cyclooctenes (sTCO) and tetrazines can achieve second...

Resource Type:

Dissertation

Full Text:

trans-cyclooctenes (sTCO) and tetrazines can achieve second order rate constants of 106 M-1s-1 or
The Development of Computational Methods for Studying Plant-Pathogen Interactions

Creator:

Pankow, Rebecca C.

Abstract:

Modern technology has enabled the advancement of biological research through the use of powerful machines and computers as well as innovative computer programs. Advances in sequencing technology and software enable us to make de novo assemblies of organism genomes, and the development of specialized computer programs can automate routine but...

Resource Type:

Honors College Thesis

Full Text:

and Melodie Putnam for their collaborative work. CONTRIBUTIONS OF CO-AUTHORS
Towards a Better Understanding of How the Dietary Supplement Xanthohumol Can Improve Health

Creator:

Logan, Isabelle E.

Abstract:

Xanthohumol, a prenylated flavonoid found in hops and beer, possesses a long-standing reputation to improve health. Xanthohumol’s cytotoxicity to a wide variety of cancer cell lines is well-established. Herein we provide further insight into the cytotoxicity of not only xanthohumol, but also its non-estrogenic derivatives, to a number of colonic...

Resource Type:

Dissertation