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Filtering by: Contributor Marquart, Grant Degree Field Biochemistry and Biophysics

Conformational transitions of nucleosome core particles monitored with time-resolved fluorescence spectroscopy

Creator:

Brown, D. W. (David W.), 1937-

Abstract:

Time-resolved fluorescence spectroscopy was used to monitor the effects of varying ionic strength on nucleosome core particle structure. Two main methods were used in these studies. First, the fluorescence anisotropy decay of bound ethidium was measured and was shown to reflect the rotational tumbling of the core particle through solution,...

Resource Type:

Dissertation

Full Text:

Training Grant GM07774, as well as from NIH Grant GM25663 throughout my studies. Special acknowledgement