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Filtering by: Creator Nandpuri, Karam Singh Remove constraint Creator: Nandpuri, Karam Singh Degree Field Biochemistry and Biophysics Remove constraint Degree Field: Biochemistry and Biophysics

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Enzyme associations in deoxyribonucleotide biosynthesis : anti-idiotypic antibodies as probes for direct protein-protein interactions

Creator:

Young, James Patrick

Abstract:

The ability to faithfully replicate DNA is dependent upon the maintenance and regulation of its precursors, the deoxyribonucleoside triphosphates. Enzymes encoded by the bacteriophage T4 have been widely used as models of biochemical processes. A body of evidence supports the concept that the bacteriophage T4 enzymes involved in deoxyribonucleotide biosynthesis...

Resource Type:

Dissertation
Bacteriophage T4 ribonucleotide reductase : genes and proteins

Creator:

Hanson, Eric Scott

Resource Type:

Dissertation

Full Text:

aspects of the molecular biology of T4 has recently been published (Karam, 1994). Following adsorption of
Alternatives to the DNA precursor-synthesizing enzyme complex hypothesis

Creator:

Weitz, Stephen L.

Abstract:

Investigators have been studying an aggregate containing enzymes of deoxyribonucleoside triphosphate biosynthesis in T4-phage infected bacteria. They suggest that it behaves as an organized complex, efficiently channeling DNA precursors to the replication apparatus. Previous work has suggested that about 10 enzyme activities remain associated through several fractionation steps. This multi-enzyme...

Resource Type:

Dissertation
Protein-protein interactions in the bacteriophage T4-coded dCTPase-dUTPase

Creator:

Ungermann, Christian

Resource Type:

Masters Thesis
Organization of the T4 dNTP synthetase complex at DNA replication sites

Creator:

Kim, JuHyun

Abstract:

With respect to a multienzyme complex of deoxyribonucleoside triphosphate (dNTP) synthesis somehow juxtaposed with DNA replication sites, our laboratory has demonstrated the existence of a multienzyme complex in T4-infected E. coli, named the T4 dNTP synthetase complex, but the idea of direct linkage of dNTP synthesis to DNA replication and...

Resource Type:

Dissertation
Organization of T4 bacteriophage genes and gene products involved in DNA precursor biosynthesis

Creator:

Wang, Yeong

Abstract:

Bacteriophage T4 gene 42 encodes dCMP hydroxymethylase, an enzyme unique to the deoxyribonucleotide metabolism of T-even bacteriophages. To study biochemical and biophysical properties of the enzyme, as well as the interaction of dCMP hydroxymethylase with other DNA precursor biosynthetic enzymes in vitro, availability of large amounts of the enzyme is...

Resource Type:

Dissertation
Nucleoside diphosphokinase of Escherichia coli and its interactions with bacteriophage T4 proteins of DNA synthesis

Creator:

Ray, Nancy Bisset

Resource Type:

Dissertation
Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

Creator:

Bernard, Mark Aguirre

Abstract:

Although the Escherichia coli host has almost all of the enzymes necessary to synthesize nucleotides needed for bacteriophage T4 DNA replication, phage genes expressed early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host DNA. Eight early enzymes and two host enzymes comprise the...

Resource Type:

Dissertation

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Academic Affiliation

Biochemistry and Biophysics8

Advisor

Mathews, Christopher K.8

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 1985 to 2005

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Committee Member

Anderson, Sonia1
Anglemier, Allen F.1
Barofsky, Douglas1
Ho, Shing1
Hsu, Victor L.1
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Creator

Bernard, Mark Aguirre1
Hanson, Eric Scott1
Kim, Juhyun1
Ray, Nancy Bisset1
Ungermann, Christian1
more Creators »

Date

Date range begin – Date range end

Current results range from 1984 to 2005

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Decade

2000-20091
1990-19995
1980-19892

Degree Field

Biochemistry and Biophysics[remove]8

Degree Level

Doctoral7
Master's1

Degree Name

Doctor of Philosophy (Ph.D.)7
Master of Science (M.S.)1

Language

English [eng]8

License

All rights reserved1

Non-Academic Affiliation

Oregon State University. Graduate School8

Peer Reviewed

No8

Resource Type

Dissertation7
Masters Thesis1

Rights Statement

Copyright Not Evaluated7
In Copyright1

Subject

Bacteriophage T47
DNA -- Synthesis4
Escherichia coli -- Genetics3
DNA replication2
Proteins -- Reactivity2
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