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Filtering by: Creator Nguyen, Andrew Degree Field Biochemistry and Biophysics

A Novel Approach to the Biochemical Analysis of Variants in the Essential DNA Mismatch Repair Protein MLH1

Creator:

Nguyen, Andrew

Abstract:

Genomic integrity is crucial for the viability and function of a cell. One key pathway that acts to maintain genomic integrity is DNA mismatch repair (MMR). MMR acts to correct base pair mismatches hat have escaped proofreading during DNA replication. The process of MMR is dependent on the protein heterodimer...

Resource Type:

Honors College Thesis

Full Text:

Andrew Nguyen Honors Thesis AN ABSTRACT OF THE