Index Catalog // ScholarsArchive@OSU

Empathy-Induced Distress: A Psychophysiological Approach

Creator:: Karabinas, Isabella M.
Abstract:: Empathy is considered a significant motivator of prosocial behavior. Increasing evidence suggests that feelings of personal distress associated with empathy may be stronger or weaker according to the form of perspective taking that an empathizer utilizes. The aim of the present study was to further quantify the stress consequences and...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Zheng Li, Committee Member, representing Psychology

Differential Binding and Structural Properties of the WWC Protein Family

Creator:: Rodriguez, Diego Javier
Abstract:: The WWC family consists of three proteins‐ KIBRA/WWC1, WWC2, and WWC3. The three proteins share a similar primary structure and interact with a common set of proteins. Each paralog contains two WW domains which recognize proline‐rich sequences of the type PPxY (P is proline, Y is tyrosine, x is any...
Resource Type:: Honors College Thesis
Full Text:: is tyrosine, x is any amino acid). WW domains adopt a three‐stranded antiparallel beta sheet fold

Sonification as a pathway to knowledge

Creator:: Fitch, Russell Alan
Abstract:: This paper explores the use of sonification, the conversion of data into sound, to convey the significance of SARS-COV-2 and its global impact. It emphasizes sonification as a valuable tool for making complex data accessible, particularly in high school education. Sonification, an interdisciplinary field, leverages the human auditory system's pattern...
Resource Type:: Honors College Thesis
Full Text:: computers cannot replicate (X. L. Zhang et al., 2014). We can interpret sounds using multiple layers of

Gene Structure and Expression of the Rice S-Domain Kinase (SD-RLK) Gene Subfamily

Creator:: Dikeman, Daemon
Abstract:: The S-domain subfamily of receptor-like kinases (SD-RLKs) in plants is poorly characterized and the majority of genes have unknown functions. The goal of this study was to study the expansion of rice (Oryza sativa) SD-RLK subfamily, and characterize gene and protein structure and expression of its members using publicly available...
Resource Type:: Honors College Thesis
Full Text:: ://www.ebi.ac.uk/ar rayexpress/experiments/ E-MTAB-2039/ http://dx.doi.org/10.1111/j .1365-313X.2012.05005.x

Short-Term Lipid Overload in Skeletal Muscle Induces Mild Mitochondrial Membrane Depolarization as a Stimulus for Autophagy Activation

Creator:: Brinck, Isabel M.
Abstract:: Type 2 Diabetes Mellitus is a chronic metabolic condition that impairs insulin stimulated glucose absorption in skeletal muscle, a characteristic phenomenon denoted as insulin resistance. Lipid overload of the mitochondria is linked to the development of insulin resistance and the progression of Type 2 Diabetes. As lipids accumulate there is...
Resource Type:: Honors College Thesis
Full Text:: . Figure X. Model of mitochondrial fission and fusion proteins. A. Mitochondrial fusion proteins Mfn2 and

Liquid-liquid Phase Separation of the Nucleocapsid of SARS-CoV-2

Creator:: Hughes, Kaitlyn
Abstract:: The nucleocapsid of SARS-CoV-2 is critical for viral genome packaging through binding to viral genomic RNA. Liquid-liquid phase separation, or LLPS, is the formation of microscopic, rapidly reversible, liquid-like immiscible droplets. There is increasing scientific evidence that LLPS underlies the formation of membraneless compartments within cells and that this process...
Resource Type:: Honors College Thesis
Full Text:: (Chen, 2020). Through X-ray crystallography and NMR, the NTD structure has been solved and it is a

The Effect of Riluzole on P2X7 and EAAT2 Expression by Inducible Neural Progenitor Cell (iNPC)-derived Astrocytes

Creator:: Sy, Kevin
Abstract:: Although it is the first drug approved for usage to treat amyotrophic lateral sclerosis (ALS), riluzole’s mechanism of action is unknown and its therapeutic quality is hampered by its relatively short window of effectiveness. P2X7 is a purine receptor found in astrocytes and other cells, which increases calcium concentrations within...
Resource Type:: Honors College Thesis

Tuning tRNA and EF-Tu for the Efficient Site-specific Incorporation of Noncanonical Amino Acids into Proteins

Creator:: Gottfried-Lee, Ilana L.
Abstract:: Genetic code expansion (GCE) is a technology that allows us to incorporate noncanonical amino acids (ncAAs) site-specifically into recombinant proteins using engineered translational machinery. Typically, an orthogonal aaRS/tRNA pair is engineered by directed evolution to recognize the ncAA and incorporate it at a reassigned codon while not interacting with the...
Resource Type:: Honors College Thesis
Full Text:: parallel with the tRNA library (theoretical library size of 206 EF-Tu x 4096 tRNAs = 260 billion members

A Comparative Analysis of U.S. News Media Coverage on Masks between the 1918 Influenza and COVID-19 Pandemics

Creator:: Nguyen, Mindy
Abstract:: Over 100 years separate the 1918 Influenza and COVID-19 pandemics, and a multitude of science, public health and communication advancements have emerged. With the COVID-19 pandemic still underway, recently reaching the one million death mark in the United States alone (CDC, 2020), researchers are searching for clues as to how...
Resource Type:: Honors College Thesis

ScholarsArchive@OSU

Empathy-Induced Distress: A Psychophysiological Approach

Differential Binding and Structural Properties of the WWC Protein Family

Sonification as a pathway to knowledge

Gene Structure and Expression of the Rice S-Domain Kinase (SD-RLK) Gene Subfamily

Short-Term Lipid Overload in Skeletal Muscle Induces Mild Mitochondrial Membrane Depolarization as a Stimulus for Autophagy Activation

Liquid-liquid Phase Separation of the Nucleocapsid of SARS-CoV-2

The Effect of Riluzole on P2X7 and EAAT2 Expression by Inducible Neural Progenitor Cell (iNPC)-derived Astrocytes

Tuning tRNA and EF-Tu for the Efficient Site-specific Incorporation of Noncanonical Amino Acids into Proteins

A Comparative Analysis of U.S. News Media Coverage on Masks between the 1918 Influenza and COVID-19 Pandemics

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