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Filtering by: Creator Shiel, A. E. Degree Field Bioengineering Degree Field Biochemistry and Biophysics

Activation and Nuclear Translocation of the Transcription Factor Nrf2 by the MAP Kinase Family

Creator:

Nguyen, Ngan H.

Abstract:

Eukaryotic cells have developed elaborate biochemical processes to counteract oxidative stress, electrophiles, or carcinogens due to environmental insults. One of these important cellular defense mechanisms is mediated by the transcription factor Nrf2 that have been shown to have decrease activity with age. While the process of which Nrf2 is involved...

Resource Type:

Honors College Thesis

Full Text:

. & Khairallah, E. A. (1998) in Toxicology of the Liver, eds. Plaa, G. L. & Hewitt, W. R. (Taylor & Francis