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Filtering by: Creator Wang, Kuen Wu Degree Field Bioengineering Degree Name Doctor of Philosophy (Ph.D.)

Engineering an Ex-Vivo System to Study Transport Phenomena in the Human Intervertebral Disc

Creator:

Shalash, Ward

Abstract:

Back pain is the leading cause of disability worldwide, entailing a significant socioeconomic impact. A primary source of back pain can be attributed to intervertebral disc (IVD) degeneration allowing nerve ingrowth, facet joint arthritis, disc bulging, and osteophyte formations that press on nearby nerve roots or the spinal cord. While...

Resource Type:

Dissertation

Full Text:

. 2017; Wang et al. 2016b; Zhou et al. 2016; Iatridis and ap Gwynn 2004). However, studies point to
Investigating the Role of Inflammation and Mechanical Loading in Orthopaedic Tissue Degeneration

Creator:

Benage, Lindsay G.

Abstract:

Orthopaedic soft tissue degenerative diseases significantly affect the population, especially as it ages. Degeneration is characterized by a progressive loss of extracellular matrix (ECM) components necessary for the proper functioning of the tissues and joints, eventually leading to pain and dysfunction. In humans, the intervertebral disc (IVD) and tendon are...

Resource Type:

Dissertation
Development of Rapid Diagnostic Tools for Personal Health Monitors in the Context of Therapy Monitoring

Creator:

Wentland, Lael T.

Abstract:

Personal health monitoring tools, a subset of point-of care-diagnostics, enable more frequent testing of chronic health conditions outside of a clinic setting and can inform personalized therapy or support telehealth diagnostic capabilities. While there is evidence that regular monitoring of chronic conditions can lead to better health outcomes and lower...

Resource Type:

Dissertation

ScholarsArchive@OSU

Engineering an Ex-Vivo System to Study Transport Phenomena in the Human Intervertebral Disc

Investigating the Role of Inflammation and Mechanical Loading in Orthopaedic Tissue Degeneration

Development of Rapid Diagnostic Tools for Personal Health Monitors in the Context of Therapy Monitoring

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