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Filtering by: Creator Loughborough, W. Karl Remove constraint Creator: Loughborough, W. Karl Degree Field Chemical Engineering Remove constraint Degree Field: Chemical Engineering Rights Statement In Copyright Remove constraint Rights Statement: In Copyright

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  • Properties of hydrogels for immobilization of bacteria in a commercial microfluidic dioreactor

    Creator:
    Weymann, Davis
    Abstract:
    Current technological shortcomings limit the economic viability of capturing and utilizing small sources of methane. The development of a reactor to overcome these limitations would unlock economic opportunity and incentivize reduced methane emissions. A microfluidic bioreactor containing immobilized methanotrophs has the potential to overcome these limitations by profitably converting small...
    Resource Type:
    Masters Thesis
    Full Text:
    Abstract approved: ______________________________________________________ Karl F. Schilke Current

  • Immobilization of Methylosinus trichosporium OB3b in a Biolamina Plate Reactor for the Oxidation of Methane to Methanol

    Creator:
    Fuchs, Brian K.
    Abstract:
    Methane is a flammable gas that is the main component of natural gas. It is a highly potent greenhouse gas, and accounts for about 20% of greenhouse gas emissions. Methane is routinely flared in many industrial processes without harnessing any of its energy. The environmental impact and wasted energy potential...
    Resource Type:
    Masters Thesis
    Full Text:
    : ______________________________________________________ Karl F. Schilke Methane is a flammable gas that is the main component of natural gas

  • Functional polymers and proteins at interfaces

    Creator:
    Schilke, Karl F.
    Abstract:
    Functional polymers and proteins at interfaces and surfaces are of fundamental importance for biomaterials, biocatalysis and microreactor applications. Candida antarctica lipase B immobilized on poly-DL-tryptophan tethers showed 30x higher specific activity in aqueous and non-aqueous media than the same enzyme adsorbed or covalently bound directly to the surface. An excess...
    Resource Type:
    Dissertation
    Full Text:
    DISSERTATION OF Karl F. Schilke for the degree of Doctor of Philosophy in Chemical Engineering

  • Binding of bacterial lipopolysaccharide by the cationic amphiphilic peptide WLBU2 at interfaces

    Creator:
    Ryder, Matthew P.
    Abstract:
    Passage of blood through a sorbent device for removal of bacteria and endotoxin by specific binding with immobilized, membrane-active, bactericidal peptides holds promise for treating severe blood infections. Peptide insertion in the target membrane and stable binding is desirable, while membrane disruption and release of degradation products to the circulating...
    Resource Type:
    Dissertation
    Full Text:
    Karl F. Schilke_ Passage of blood through a sorbent device for removal of bacteria and endotoxin by

  • Molecular origins of peptide entrapment in polyethylene oxide layers

    Creator:
    Wu, Xiangming
    Abstract:
    A more quantitative understanding of peptide entrapment and elution from otherwise protein-repellent polyethylene oxide (PEO) brush layers will provide direction for development of new strategies for drug storage and delivery. Here we describe criteria for peptide integration and structural change within the PEO brush, and discuss the reversibility of peptide...
    Resource Type:
    Dissertation
    Full Text:
    : _____________________________________________________________________ Joseph McGuire Karl F. Schilke A more quantitative understanding of

  • Transient Microrheological Characterization of Biogels

    Creator:
    Mao, Yating
    Abstract:
    The Brownian motion of micron-scale particles reflects the viscoelastic response of the local environment of the medium. Tracking the thermal fluctuations of these particles is a measure of the rheology of the material at the microscopic scale. This technique is called passive microrheology. Microrheology has been developed to assess the...
    Resource Type:
    Masters Thesis
    Full Text:
    Microrheological Characterization of Biogels Abstract approved: Travis W. Walker The Brownian motion of micron

  • Probing the Biophysical interactions of Anti-Microbial Peptide WLBU2 Using Model Membrane Systems

    Creator:
    Golbek, Thaddeus W.
    Abstract:
    WLBU2 is an engineered cationic amphiphilic peptide that targets Gram-positive and Gram-negative bacteria, and envelopes endotoxin while avoiding other cell types. The exact mechanism of how WLBU2 targets, binds, and disrupts bacterial cell membranes is still not completely known. Thus, the overall goal of this investigation is to determine the...
    Resource Type:
    Masters Thesis
    Full Text:
    AN ABSTRACT OF THE THESIS OF Thaddeus W. Golbek for the degree of Master of Science in Chemical

  • SwannBritanyM2017.pdf

    Creator:
    Swann, Britany and Swann, Britany M.
    Abstract:
    Additive manufacturing and 3D printing have become household names as both hobbyistsand industrial manufacturers utilize fast, inexpensive prototyping and production of functionalparts. Additive manufacturing is being revolutionized with 3D printers such as theMulti Jet Fusion 3D from HP, Inc., where each volume pixel, or voxel, can be independentlyfunctionalized. Voxel-by-voxel printing...
    Resource Type:
    Masters Thesis
    Full Text:
    Abstract approved: Travis W. Walker Additive manufacturing and 3D printing have become household names as

  • Synthesis and evaluation of PEO-coated materials for microchannel-based hemodialysis

    Creator:
    Heintz, Keely
    Abstract:
    The marked increase in surface-to-volume ratio associated with microscale devices for hemodialysis leads to problems with hemocompatibility and blood flow distribution that are more challenging to manage than those encountered at the conventional scale. In this work, stable surface modifications with pendant polyethylene oxide (PEO) chains were produced on polycarbonate...
    Resource Type:
    Masters Thesis
    Full Text:
    learning experience! Thanks to my second-in-line (but not least!) advisor Dr. Karl “Rat” Schilke for

  • CO₂ Reduction in Microscale-Based Corona Reactor : Experiments and Modeling

    Creator:
    Miao, Yu
    Abstract:
    Global warming is becoming an increasingly important environmental concern and CO₂ is considered as the major cause of global warming. Creating useful applications for CO₂ would generate alternatives to merely venting CO₂ to the atmosphere, and decreasing the carbon intensity of human activities. Among various methods of CO₂ utilization, conversion...
    Resource Type:
    Dissertation
    Full Text:
    Dr. Liney Árnadóttir, Dr. Karl Schilke and Dr. Morrie Craig for participating as committee members