Index Catalog // Hyrax

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

Schöpfer:: Koluda, Rony
Abstract:: Radiation exposure to the brain can occur from a variety of events, including space missions, nuclear accidents, and clinical treatments. The effects of high dose radiation are well studied, but those of lower dosage are more elusive. Decline of memory and cognition is observed in patients exposed to low dose...
Resource Type:: Masters Thesis

A Reversible Conversion Cathode – Convert Dual-ion Battery into Rocking-Chair Battery

Schöpfer:: Wu, Che-Yu
Abstract:: In Dual-ion Batteries, anions as charge carriers might be a potential technique of energy storage. While fluoride anion has been selected as a promising charge carrier for energy storage due to its high charge/mass ratio and small ionic radius, carbonate anion has never been reported as a charge carrier for...
Resource Type:: Masters Thesis

Alternating Between Amperometric Copper Detection and Potentiometric Calcium Detection on a Carbon-based Ion-selective Electrode

Schöpfer:: Park, Suji
Abstract:: The unique capability of carbon-based ion-selective electrode (ISE) to perform highly sensitive anodic stripping voltammetry, while maintaining all the properties of an ISE, is demonstrated in terms of sensitivity, detection limit, response time and selectivity. Square wave anodic stripping voltammetry involves deposition and dissolution steps of metal ions, which means...
Resource Type:: Masters Thesis

Total Synthesis of Isotopologues of Xanthohumol and its Congeners for Biological Studies

Schöpfer:: Plagmann, Layhna S.
Abstract:: Xanthohumol [XN, (E)-6´-methoxy-3´-(3-methylbuten-2-yl)-2´,4´,4´´-trihydroxychalcone], the principal prenylated chalcone from hops, and its 2,3-dihydro- (DXN) and O6-desmethyl-2,3-dihydro- (DDXN) congeners, are of potential utility for the amelioration of metabolic syndrome; however, their complex bioactivity profiles cannot be properly studied and understood without access to appropriately produced synthetic materials. In the first part of...
Resource Type:: Masters Thesis

Using Computational and Statistical Methods as an Aid to Study Environmentally Relevant Organic Molecules

Schöpfer:: Dorn, Shelby E.
Abstract:: In this report, three studies are presented that utilize computations to predict transformations, identities, and properties of environmental organic molecules. Each study shows how computations can lead to models of chemical behavior. The importance of this research is rooted in the need for understanding how human behavior and health intersect...
Resource Type:: Masters Thesis

Using Computational Methods to Elucidate Reaction Mechanisms for Copper Catalyzed Reactions

Schöpfer:: Caspary, Katherine E.
Abstract:: In this report, two studies are presented that utilize computations to predict and elucidate the reaction mechanisms of two different copper catalyzed reactions. Each study provides insight into the various chemical transformations, as well as the how and why behind regioselectivity and isotopic selectivity. The importance of this research is...
Resource Type:: Masters Thesis

Bioprospecting the Chemical Diversity of Plant-associated Fungi

Schöpfer:: González-Montiel, Gisela Abigail
Abstract:: Fungi have long been used for discovery of new chemical scaffolds. In the clinical setting, the fungal natural products penicillin, statins, and cyclosporine have revolutionized medicine to treat diseases and infections. In the environment, fungal natural products have been used as herbicides, fungicides, and insecticides to protect crops, livestock, and...
Resource Type:: Masters Thesis

Suspect Screening of Hydrocarbon surfactants in AFFFs and AFFF-Contaminated Groundwater by High Resolution Mass Spectrometry

Schöpfer:: Garcia, Raymmah A.
Abstract:: Aqueous film forming foams (AFFFs) are proprietary mixtures containing hydrocarbon surfactants and per-and polyfluoroalkyl substances (PFASs) that are used to extinguish hydrocarbon-based fuel fires. There is limited information on hydrocarbon surfactants in AFFFs and AFFF-contaminated groundwater even though they are more abundant (5-10% w/w) than PFASs (0.9-1.5% w /w) in...
Resource Type:: Masters Thesis

Insights into Cytostatic and Cytotoxic Properties of the Natural Product Mensacarcin

Schöpfer:: Kaweesa, Elizabeth Namagoba
Abstract:: Mensacarcin is a stereogenic complex polyketide with potent anti-tumor activity produced by a soil-dwelling Streptomyces bottropensis. The US National Cancer Institute (NCI) 60 human tumor cell line anticancer drug screen (NCI-60) reveals mensacarcin’s cytostatic properties in almost all tested cell lines and distinct cytotoxic properties specifically in eight melanoma cell...
Resource Type:: Masters Thesis

Identification, Quantification, and Risk Assessment of Polycyclic Aromatic Hydrocarbons and their Derivatives in Soil after Steam Enhanced Extraction

Schöpfer:: Santiago Delgado, Lisandra
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are environmental contaminants produced mainly from the incomplete combustion and pyrolysis of organic matter. PAHs are among the major contaminants at over 800 Superfund sites, nationwide. Thermal remediation is used as a method to remediate soils contaminated with PAHs through the use of heat to mobilize...
Resource Type:: Masters Thesis

Hyrax

Low-Dose X-Ray Radiation Effects On the Proteomic Profiles of Hippocampus, Cortex, and Cerebellum of Contextual Fear Conditioning and Novel Object Recognition Trained Mice

A Reversible Conversion Cathode – Convert Dual-ion Battery into Rocking-Chair Battery

Alternating Between Amperometric Copper Detection and Potentiometric Calcium Detection on a Carbon-based Ion-selective Electrode

Total Synthesis of Isotopologues of Xanthohumol and its Congeners for Biological Studies

Using Computational and Statistical Methods as an Aid to Study Environmentally Relevant Organic Molecules

Using Computational Methods to Elucidate Reaction Mechanisms for Copper Catalyzed Reactions

Bioprospecting the Chemical Diversity of Plant-associated Fungi

Suspect Screening of Hydrocarbon surfactants in AFFFs and AFFF-Contaminated Groundwater by High Resolution Mass Spectrometry

Insights into Cytostatic and Cytotoxic Properties of the Natural Product Mensacarcin

Identification, Quantification, and Risk Assessment of Polycyclic Aromatic Hydrocarbons and their Derivatives in Soil after Steam Enhanced Extraction

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