Index Catalog // ScholarsArchive@OSU

Computational Rationalizations of Mechanism and Stereocontrol in Small-Molecule Lewis Base Organocatalysis

Creator:: McCauley-Walden, Daniel W.
Abstract:: My work has focused on investigating synthetic organic reactions using applied computational methods. Non-covalent interactions are critical to catalysis, mechanism, and stereoselectivity, with the most prominent interaction for isothioureas being the S···O contact between the catalyst sulfur atom and the oxygen of the acyl group. A comprehensive joint experimental and...
Resource Type:: Dissertation
Full Text:: , a C–H···O between the substrate and the catalyst oxygen atom favors lactonization. Computed TSs

The development of a high spectral-resolution laser-excited molecular fluorescence system and its application to gas chromatography and the determination of polynuclear aromatic hydrocarbons

Creator:: Hein, Scott J.
Abstract:: A high-spectral resolution laser-excited molecular fluorescence system was developed that utilizes a pulsed supersonic expansion to simplify the fluorescence excitation spectra of large, gas-phase aromatic molecules diluted in an excess of a monatomic gas. A microcomputer was used to control and synchronize the instrumental components, which included a Chromatix CMX-4...
Resource Type:: Dissertation
Full Text:: DETERMINATION OF POLYNUCLEAR AROMATIC HYDROCARBONS Redacted for Privacy Abstract approved: E. H. Piepmeier A

GaAs(100) surface chemistry : interactions with molecular chlorine and sulfur compounds

Creator:: Mokler, Scott M.
Abstract:: An important aspect in device technology is the processing of GaAs to produce highly-resolved etch patterns on the substrate. This is done typically on the GaAs(100) surface. Recently, a number of methods, all using chlorinated vapor reactants, have been applied to fabrication of GaAs devices. In spite of these technological...
Resource Type:: Dissertation
Full Text:: , are always there looking out for me. Finally, and most importantly, I thank Linda, my friend

Investigation of Chain Extension Approaches for the Stereoselective Reagent-Controlled Synthesis of alpha-Heteroatom Substituted Alkyl Boronic Esters

Creator:: Barsamian, Adam L.
Abstract:: Two distinct strategies were explored for the enantioselective synthesis of α-heteroatom substituted alkyl boronic esters by stereoselective reagent-controlled homologation using transient chiral carbenoid reagents CHYMX (Y = heteroatom, X = nucleofuge, M = electrofuge). In the first case, a stereospecific reagent-controlled homologation (sStReCH) approach to α-alkoxyalkylboronates using α-metalated S,O- and...
Resource Type:: Dissertation
Full Text:: (≤ 2.5 h, at –78 °C) stereodefined α-magnesiated S,O-acetals 103 that incorporated D-atoms in a

Fusion enhancement with neutron-rich radioactive beams

Creator:: Zyromski, Kristiana Elizabeth
Abstract:: Fusion reactions with radioactive neutron-rich projectiles have been the subject of much recent theoretical and experimental interest. Predictions of enhancement of the cross section due to the use of a neutron-rich projectile may have implications for synthesis of heavy nuclei. In this work, the fusion-fission excitation functions were measured for...
Resource Type:: Dissertation
Full Text:: . . . . . . . . . . . . . .. 80 3.13 Comparison of observed laboratory folding angles with predictions of the code LINDA

Wide band gap semiconductors and insulators : synthesis, processing and characterization

Creator:: Hersh, Peter A.
Abstract:: The work presented here is focused on applying basic principles of solid-state chemistry to the study and development of new wide band-gap semiconductors and insulators for photovoltaic and electronic-device applications. Analysis of crystal structure, band structure, optical band gap, morphology and transport properties provides fundamental insight into materials performance as...
Resource Type:: Dissertation
Full Text:: also like to thank the office staff, especially Joey Carson, Linda Adams, and Cindy Persson

Synthesis of furanoeremophilane sesquiterpenoids

Creator:: Shanmugham, Meenakshi Sundaram
Abstract:: Two approaches to the tricyclic core of the furanoeremophilane sesquiterpenoids are described. The first approach entails a projected Diels-Alder/retro Diels-Alder reaction of an acetylenic oxazole 64. Construction of the pivotal aldehyde 67 commenced from ketone 68. The acetyenic moiety was then introduced via a Felkin-Ahn addition of lithiopropyne to aldehyde...
Resource Type:: Dissertation
Full Text:: , Nick Drapela, Uwe Grether, Roger Hanselmann, Josh Hansen, Bryan Hauser, David IhIe, Scott Kemp, Linda

Studies toward the total synthesis of phorboxazole A

Creator:: Kuntiyong, Punlop
Abstract:: Studies toward the total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, were conducted and resulted in a route to an advanced intermediate, C4-C32, for this purpose. A key feature of our approach is the stereoselective synthesis of two cis-2,6-disubstituted tetrahydropyrans present in the macrolide portion of...
Resource Type:: Dissertation
Full Text:: Hansen, Carla Hassler, Bryan Hauser, Eric Hong, Peter Hrnciar, Scott Kemp, Linda Keown, Jungchul Kim

Studies towards the total syntheses of (+)-phomactins A, D and G

Creator:: Schwartz, Keith D.
Abstract:: Studies towards the total synthesis of (+)-Phomactin A (1), D (6), and G (9), fungal metabolites with unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 354 and 356, which contain all of the carbon atoms of 1, 6 and 9....
Resource Type:: Dissertation
Full Text:: . Laura Mace Kristi Edwards Joey Carson, Dr. Kris Wayant Dr. Jeff Walker Linda Adams Alchemist

Total synthesis of indole alkaloids: pt. 1. Asymmetric synthesis of (-)-ibogamine. pt. 2. An approach toward the synthesis of koumine

Creator:: Choi, Younggi
Abstract:: PART I. The preparation of (-)-ibogamine (1) in fourteen steps from benzoquinone and in 10% overall yield is a powerful illustration of the value of the asymmetric Diels-Alder reaction as a starting point in a multistep synthesis. All four cycloadducts, 70, 77, 84 and 96, obtained with the (S)-BINOL-TiCl₂ complex...
Resource Type:: Dissertation
Full Text:: , Scott J. Kemp, Linda E. Keown, Jungchul Kim, Sung-kee Kim, Eric A. Korf, Christian L. Kranman, Punlop

ScholarsArchive@OSU

Computational Rationalizations of Mechanism and Stereocontrol in Small-Molecule Lewis Base Organocatalysis

The development of a high spectral-resolution laser-excited molecular fluorescence system and its application to gas chromatography and the determination of polynuclear aromatic hydrocarbons

GaAs(100) surface chemistry : interactions with molecular chlorine and sulfur compounds

Investigation of Chain Extension Approaches for the Stereoselective Reagent-Controlled Synthesis of alpha-Heteroatom Substituted Alkyl Boronic Esters

Fusion enhancement with neutron-rich radioactive beams

Wide band gap semiconductors and insulators : synthesis, processing and characterization

Synthesis of furanoeremophilane sesquiterpenoids

Studies toward the total synthesis of phorboxazole A

Studies towards the total syntheses of (+)-phomactins A, D and G

Total synthesis of indole alkaloids: pt. 1. Asymmetric synthesis of (-)-ibogamine. pt. 2. An approach toward the synthesis of koumine

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