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Filtering by: Creator Jackson, Alexis M. Degree Field Chemistry Resource Type Honors College Thesis

A robust Mycobacterium smegmatis Assay for the Discovery of Anti-tubercular Metabolites from Soil Bacteria

Creator:

Chen, Kathryn P

Abstract:

Tuberculosis (TB) is a pressing global health issue with approximately one third of the world’s population infected by this bacterium. As one of the most dangerous infectious diseases, it has killed approximately 1.7 million people of all ages around the world per year (World Health Organization, 2016). Currently, several drugs...

Resource Type:

Honors College Thesis

Full Text:

products, drug discovery, antitubercular, M. smegmatis Corresponding e-mail address: chenka
Bioactivity Screening and Gene Activation Strategies in Fungi

Creator:

Coddington, Nathan C.

Abstract:

Natural products from plants, bacteria, and fungi play an important role in society. Over the last 35 years, natural products and their derivatives have inspired over 60% of all FDA approved small-molecule drugs, and are among the top prescribed therapeutics.1-2 Fleming’s discovery of the fungal antibiotic penicillin started the “Golden...

Resource Type:

Honors College Thesis

Full Text:

information was used to assign unique values based of the retention time, m/z value, and abundance of all