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Filtering by: Creator Zimbelman, James R. Remove constraint Creator: Zimbelman, James R. Degree Field Chemistry Remove constraint Degree Field: Chemistry Rights Statement Copyright Not Evaluated Remove constraint Rights Statement: Copyright Not Evaluated

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  • Electrochemical studies of liquid chlorocuprates(I)

    Creator:
    Silkey, James R.
    Abstract:
    This research emphasized fundamental physical and electrochemical studies of systems based on the room temperature fused salt, triethyl-ammonium dichlorocuprate(I). Such systems, which must be maintained under a protective atmosphere, were also used in some preliminary battery studies. Spectra of dark green solutions of copper (II) chloride in triethylammonium dichlorocuprate(I) obey...
    Resource Type:
    Masters Thesis
    Full Text:
    ABSTRACT OF THE THESIS OF James R. Silkey for the degree of Master of Science in Chemistry presented on

  • Reactions of I-(α-pyridyl)-3-buten-1-o1

    Creator:
    Whitman, James Edgar
    Abstract:
    The purpose of this project was to study the reactions of 1-(α-pyridyl)-3-buten-1-ol (compound I) and to determine whether or not the products of some of its reactions are quinolizinium salts. Reaction of compound I with bromine or iodine yields halide salts (when no external cooling is applied) instead of the...
    Resource Type:
    Masters Thesis
    Full Text:
    . M. R. identification has yet been rnade, Z) identification of soryre of the irnportant I. R. bands

  • Synthesis of a model of the spiroketal portion of avermectin B

    Creator:
    Warrier, Ulhas S.
    Abstract:
    Avermectin Bia is a member of a class of medicinally important natural products known for its potent antiparasitic activity and interesting structural features. In this thesis, synthesis of a model for the spiroketal portion of the avermectins is presented. Oxidation of (S)-2-methylbutanol, followed by a stereoselective chromium mediated reaction with...
    Resource Type:
    Masters Thesis
    Full Text:
    Bla Abstract approved: Redacted for privacy r Dr. James D. White Avermectin Bia is a member of a

  • Synthesis and oxidation of metal-thiolate compounds which mimic the active site function of thiolate dioxygenase enzymes

    Creator:
    Schussel, Leonard J.
    Abstract:
    Part I describes the synthesis of bis(fac-S)((tris)2-aminoethanethiolatoiron( III))iron(III) chloride. The compound was first discovered during an attempt to prepare a ternary complex of iron, thiolate and pi-acid ligand. The compound is a reasonably air-stable iron(III)-thiolate that contains a linear tri-iron cluster with each iron bridged to the adjacent iron by...
    Resource Type:
    Dissertation
    Full Text:
    DIOXYGENASE ENZYMES Abstract approved: Redacted for Privacy Dr. James H. Krueger Part I describes the

  • Reactions and stereochemistry of thiolato and sulfenato cobalt (III) complexes

    Creator:
    Herting, Daniel L.
    Abstract:
    This thesis describes a study of the synthesis, stereochemistry, and reactivity of cobalt(III) cysteinato (CyS) and related thiolato complexes. The preparation of [Co(en)₂CyS]⁺ resulted in a product solution containing a mixture of diastereomers in the ratio 2.3:1 (Δ:A). The isomers were separated by ion exchange chromatography, and their absolute configurations...
    Resource Type:
    Dissertation
    Full Text:
    A-[Co(en)2CyS] + by H202 led to a 2.9 :1 (S:R) mixture ofAS- and AR- { Co(en)2(CyS0)1+, the S and R

  • Studies on the synthesis of the "northern" and "southern" segments of boromycin and aplasmomycin

    Creator:
    Kang, Myung Chol
    Abstract:
    The stereocontrolled synthesis of the southern lactone 17 of boromycin and of the northern segments of both boromycin and aplasmomycin are described. The syntheses begin with enantioselective epoxidation of 3-buten-2-ol (42) to provide the optically active 2(S),3(R) epoxy alcohol 43. The absolute configuration was confirmed by preparing 43 from (-)-2,3-dihydroxybutyric...
    Resource Type:
    Dissertation
    Full Text:
    for privacy Dt. James D. White The stereocontrolled synthesis of the southern lactone 17 of

  • Synthesis of metabolites from the ascomycetes : I. The synthesis and absolute configuration of leptosphaerin : II. Approaches to the synthesis of byssochlamic acid

    Creator:
    Pallenberg, Alexander J.
    Abstract:
    Part I. The total synthesis of (+)-leptosphaerin (2), a metabolite of the marine Ascomycete Leptosphaeria Oraemaris (Linder) was achieved, unambiguously establishing both the relative and absolute stereochemistry of this natural product. This synthesis also resolved the long-standing question of which of the isomeric structures 1 or 2 correctly represents the...
    Resource Type:
    Dissertation
    Full Text:
    Redacted for privacy Abstract approved: James D. White Part I. The total synthesis of (+)-leptosphaerin

  • Approaches to the synthesis of methymycin

    Creator:
    Raghavan, Palaykotai Rajagopalan
    Abstract:
    Several approaches to the synthesis of methymycin were investigated. Segment A (39), containing functionality corresponding to C-9, 10, and 11 of methynolide was made in six steps from propionaldehyde in an overall yield of 37%. Oxidation of 34 with silver nitrate gave 35 which, upon hydroxylation with hydrogen peroxide, gave...
    Resource Type:
    Dissertation
    Full Text:
    approved: Dr. James D. White Several approaches to the synthesis of methymycin were investigated

  • Absolute stereochemistry and total synthesis of botryococcene

    Creator:
    Reddy, Guvvala Nagabhushana
    Abstract:
    Studies were carried out to determine the absolute stereochemistry of botryococcene (1). The natural product was degraded to two sets of 'y- and 8- valerolactones. All enantiomeric variations of these lactones were synthesized in optically pure form starting from (S)- and (R)-methyloxiranes. 1H NMR correlation of natural and synthetic materials...
    Resource Type:
    Dissertation
    Full Text:
    Botryococcene Abstract approved: Pedacted for Privacy Li James D. White Studies were carried out to determine

  • Synthesis of two subunits of avermectin B1a

    Creator:
    Dantanarayana, Anura Pathmasiri
    Abstract:
    Avermectins are a group of potent anthelmintic agents produced by Streptomyces avermitilis. They are active at extremely low dosages and are now in commercial use. In this study, the synthesis of two segments of avermectin B[subscript 1a] are described. The synthesis of the hexahydrobenzofuran subunit (segment A) began with the...
    Resource Type:
    Dissertation
    Full Text:
    approved: Redacted for privacy (it James D. White Avermectins are a group of potent anthelmintic agents