Index Catalog // ScholarsArchive@OSU

Investigation of Chain Extension Approaches for the Stereoselective Reagent-Controlled Synthesis of alpha-Heteroatom Substituted Alkyl Boronic Esters

Creator:: Barsamian, Adam L.
Abstract:: Two distinct strategies were explored for the enantioselective synthesis of α-heteroatom substituted alkyl boronic esters by stereoselective reagent-controlled homologation using transient chiral carbenoid reagents CHYMX (Y = heteroatom, X = nucleofuge, M = electrofuge). In the first case, a stereospecific reagent-controlled homologation (sStReCH) approach to α-alkoxyalkylboronates using α-metalated S,O- and...
Resource Type:: Dissertation
Full Text:: Investigation of Chain Extension Approaches for the

Total synthesis of phorboxazole A

Creator:: Lee, Tae Hee
Abstract:: The total synthesis of a highly potent cytotoxic marine natural product, phorboxazole A, is described. Both a palladium(II)-mediated and a palladium(II)-catalyzed intramolecular alkoxycarbonylation were used as key steps for the preparation of the two cis-2,6-disubstituted tetrahydropyran rings (C22-C26 and C11-C15) of phorboxazole A. The synthesis used a convergent approach involving...
Resource Type:: Dissertation
Full Text:: (129). Assembly of two subunits, 130 and 131, employed Evans coupling protocol and provided 141 in

Water and methanol adsorption on a series of organic complexes of montmorillonite

Creator:: Carter, Loren Sheldon
Abstract:: Water and methanol adsorption isotherms at 25° and 37° C. were determined on a series of organo-bentonite clays. The clays differed in the length of the carbon chain attached to the amine adsorbed in the cation exchange position. The amines used had carbon chains of 4, 6, 8, 10, 12,...
Resource Type:: Masters Thesis
Full Text:: about one millimeter extension per milligram of load. The isotherms were typical type II isotherms and

Development of Methods for Stereoselective Carbon-Carbon Bond Formation

Creator:: Wu, Zhenhua
Abstract:: Three distinct methods to achieve the stereoselective synthesis of carbon-carbon bonds were investigated, encompassing: (i) the formation of axially chiral biaryl molecules by enantioselective Suzuki cross-coupling, (ii) the synthesis of α-phenylalkylboronic esters by enantioselective chain extension, and (iii) the stereospecific synthesis of alkenes by eliminative cross-coupling of enantioenriched sp³-hybridized carbenoids....
Resource Type:: Dissertation
Full Text:: enantioselective chain extension, and (iii) the stereospecific synthesis of alkenes by eliminative cross-coupling

The normal vibrational analysis of polyacetaldehyde

Creator:: Lee, Dorothy
Abstract:: A method of calculating the normal vibrations of polymer molecules is presented in detail. The method is based on that used by Schachtschneider and Snyder in their analysis of polypropylene but has not heretofore been published. The factoring of the infinite matrix and reduction to the coordinates of the unit...
Resource Type:: Dissertation
Full Text:: rnolecules to rnake the extension to polyrner rnolecules by this rnethod. The geometry of polyrner chains

Sorption by detached organic films and its relation to filiform corrosion

Creator:: Kennedy, George Hunt
Abstract:: The rate of interaction of carbon dioxide with eight detached organic films commonly used as coatings for metal surfaces was examined. The films studied were lacquers of several different formulations including oleoresinous, phenolic, vinyl, alkyd, epoxy, and hydrocarbon types. The sorption was measured on a McBain type gravimetric adsorption balance...
Resource Type:: Dissertation
Full Text:: . The present work is an extension of this study. 8 Eight films were used in this series of

Synthesis, characterization, and analysis of nitroaromatic compounds

Creator:: McIntosh, Melissa Luana
Abstract:: Nitroaromatic compounds have important chemical applications and can be found in nature as pollution sources. Synthetic nitroaromatic compounds have been used in a variety of materials including explosives, pharmaceuticals, dyes, plastics, and pesticides. These compounds can find their way into the environment through normal or improper disposal methods. Poly-aromatic compounds...
Resource Type:: Masters Thesis
Full Text:: extension of this methodology to the synthesis of heterocycles such as poly-aromatic triazoles and

Studying fusion reactions for effect of PCN on heavy nucleus formation and for nuclear structure effects

Creator:: Naik, Radhika
Abstract:: The fusion reaction ²⁰⁸Pb (⁵⁰Ti, xn) ²⁵⁸⁻x Rf (x = 1-3) was studied to determine PCN (probability that the mononucleus system evolves to form a compound nucleus inside the fission saddle point) and to establish the value of Wsur (survival probability) for the given reaction experimentally. The fission excitation function...
Resource Type:: Dissertation
Full Text:: larger than 2.5fm given by 1/30 AR × . This extension of the radius is attributed to the presence of

Stereospecific Synthesis of Stereotriad Motifs and Alkenes Using Enantioenriched sp³-Hybridized Carbenoids

Creator:: Xun, Sun
Abstract:: Enantioenriched sp³-hybridized carbenoid reagents CR1R2MX (X = nucleofuge, M = electrofuge) of different types were investigated for the synthesis of polysubstituted alkyl chains by iterative stereospecific reagent-controlled homologation (StReCH) and for the stereospecific connective synthesis of alkenes by eliminative cross-coupling. In the first part, putative enantioenriched α-chloroalkyllithiums (CHRLiCl) were employed...
Resource Type:: Dissertation
Full Text:: contiguous stereotriad motif were separately targeted by triple chain extension of B-phenethyl boronic

Dynamics and Design of Green Fluorescent Protein-Inspired Superphotoacids and Red-Emitting Fluorophores with Transient Absorption and Femtosecond Stimulated Raman Spectroscopy

Creator:: Chen, Cheng
Abstract:: In the past decades, femtosecond stimulated Raman spectroscopy (FSRS) has been gaining tremendous popularity in fundamental sciences stemming from chemistry to biology. It is capable of capturing both equilibrium and non-equilibrium structural information across a broad range of timescales with simultaneously high temporal and spectral resolutions. Femtosecond transient absorption spectroscopy...
Resource Type:: Dissertation
Full Text:: require large π-conjugation extension and hence provides space for further chemical engineering for

Surface areas of graphite regenerated from graphite oxide

Creator:: Vander Zanden, Eugene Justin
Resource Type:: Masters Thesis
Full Text:: measuring the extension of the spring. This was done with a cathetometer sighted on one of the markings

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Creator:: Shaw, Subrata
Abstract:: This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Resource Type:: Dissertation
Full Text:: enantiomeric excess. Extension of this reaction to vinylic halides using the same catalyst is probed but

Studies on the mechanism of formation of n-phenylpyridinium salts from 1,7-diaza-1,3,5-heptatrienes

Creator:: Shahidi, Iraj Khatib
Resource Type:: Dissertation
Full Text:: : I H ll'hPh Mechanism A is an extension of the abnormal o-alkylation type aldol addition of

Mass-Spectrometric Methods for OxPTM Characterization and Quantitative Proteomics of Oxidative Stress Response

Creator:: Huang, Lin
Abstract:: Oxidative stress is deﬁned as an imbalance that favors the production of reactive oxygen species (ROS) over an organism's antioxidant defense. ROS have the ability to damage, either directly or indirectly, biomolecules including DNA, proteins, carbohydrates, and lipids. Various pathological conditions and environmental and chronic diseases have been associated with...
Resource Type:: Dissertation
Full Text:: ) irradiation The extension of the protocol to a multiplex MRMHR assay was allowed determining level

Development of Carbenoid Eliminative Cross-coupling for the Stereocontrolled Synthesis of Trisubstituted Alkenyl Moieties Within Styrenes and 1,3-Dienes

Creator:: Tanpure, Subhash D.
Abstract:: Traditional approaches for the direct preparation of alkenes are unable to fully control either the stereochemical configuration of the carbon-carbon double bond or else the regiochemistry of the substituents surrounding it. The recently introduced concept of carbenoid eliminative cross-coupling (CEXC) offers a remedy to these deficiencies by providing for a...
Resource Type:: Dissertation
Full Text:: -glycoprotein inhibitor) is described alongside a novel extension of the methodology to access

The microstructure of marine sediments

Creator:: Stump, Arthur Darrell
Abstract:: The surface areas and pore size distributions of a series of terrigenous marine sediments were measured by gas adsorption. The sediment samples were taken from the continental terrace off the coast of Oregon near Newport. Sampling stations ranged up to 35 miles off shore between 44°20' and 45° north latitude....
Resource Type:: Dissertation
Full Text:: extension per mg load and with a capacity of 1+00 mg. The samples were contained in small buckets shaped

Hydrogen abstraction from substituted t-butylbenzenes

Creator:: Harvey, Robert Louis
Abstract:: A study of the relative rates of the alkyl hydrogen abstraction from a series of meta and para substituted t-butylbenzenes by the chlorine atom at 70°C has been carried out. Application of the Hammett equation yielded a ρ value of -0.44 for the para compounds. Possible explanations for the non-linearity...
Resource Type:: Masters Thesis
Full Text:: direction of the group dipole and the extension of the carbon - substituent bond and R the distance

Thermodynamic properties of the chloride and fluoride salts of zirconium and hafnium dissolved in molten salt solvents

Creator:: Megy, Joseph Allen
Resource Type:: Dissertation

Synthesis and investigation of layered oxides with honeycomb ordering

Creator:: Schmidt, Whitney L.
Abstract:: Synthesis and discovery lies at the core of every field in chemistry. The investigation of the structure-property relationships in compounds known or new is the fundamental purpose of solid state chemistry. Mixing related solid state compounds to form solid solutions can lead to exciting new and/or unexpected properties. Layered compounds...
Resource Type:: Dissertation
Full Text:: .......................................................................................................... 141 A.1 Experimental Setup

The rearrangement of 1, 1-dimethyl-2-oxo-1, 2-dihydronaphthalene

Creator:: Stephenson, John Louis
Resource Type:: Masters Thesis
Full Text:: t he oxygen function . An extension of Arnold ' s mechanism to there ar~"'angement of 1 , 1- d

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