The production of C¹⁴O₂ metabolized from glucose labeled in
specific carbon atoms by homogenates of chick embryonic and adult
heart was compared by the radiorespirometric technique. Homogenates
of early (two to five days of incubation) embryo hearts were
found to utilize the phosphogluconate pathway of glucose catabolism
to a greater...
Isocitrate-NADP oxidoreductase activity in mitochondrial and
soluble fractions was determined for hearts, livers and brains of
chick embryos at various stages of development. One-half to two-thirds
of the activity in brain and liver homogenates is located in the
soluble fraction. Supernatant activity increases in these organs to a
maximum during...
Levels of activity of glucose-6-phosphate- , 6-phosphogluconate- , and isocitric- dehydrogenase were measured in the
soluble and particulate fractions of heart, brain and liver at
several ages throughout the development of the chick embryo.
Compared to isocitric dehydrogenase, levels of glucosesphosphate-
, and 6-phosphogluconate- dehydrogenase are generally
low. This suggests...