Three areas of liquid state theory are considered.
First, Monte Carlo computer simulation of a two-dimensional hard
disk fluid with an imbedded ellipse was undertaken to determine how a
non-spherical molecule affects intermolecular ordering. The
elliptical molecule (with axial ratios of 2, 5 and 10) altered the
isotropic distribution of...
The rate of the C¹⁴0₂ release from glucose, specifically labeled
with C¹⁴ at 1, 2, 3+4, and positions, was used to study the relative
participation of pathways of glucose catabolism in red beet slices.
Evidence was obtained which indicated that in mature red beets glucose
was catabolized mainly via glycolysis-tricarboxylic...
In this dissertation, my research work on excited state dynamics of small organic molecules in solutions is presented. Using femtosecond stimulated Raman spectroscopy (FSRS) as the main experimental tool, the excited state hydrogen-bonding dynamics (ESHBD) of Coumarin 102, a common laser dye molecule, in ethanol solution is examined with <150...
Complex organic transformations, such as the addition of pyrrole to ketene using planar chiral organocatalyst (*PPY), the four-component anhydride- Manniach reactions, and the site-selective desymmetrization of meso-1,2-diol, are remarkable synthetic reactions that provide high yield and high selectivity. However, the exact mechanism and origins of stereocontrol for theses synthetic organic...
Ambifunctional axially chiral 2,2',6,6'-tetrasubstituted biphenyls containing nucleophilic (or basic) functional groups juxtaposed with hydrogen-bond donors were synthesized and their properties studied. Applications for the prepared biaryls as potential organocatalysts for enantioselective carbon-carbon bond forming reactions were examined. Processes investigated included: aldol, Michael, nitroaldol (Henry), and Baylis-Hillman reactions.
The novel amidoamine...