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Filtering by: Committee Member Kolluri, Siva Kumar Degree Field Chemistry

Insights into Cytostatic and Cytotoxic Properties of the Natural Product Mensacarcin

Creator:

Kaweesa, Elizabeth Namagoba

Abstract:

Mensacarcin is a stereogenic complex polyketide with potent anti-tumor activity produced by a soil-dwelling Streptomyces bottropensis. The US National Cancer Institute (NCI) 60 human tumor cell line anticancer drug screen (NCI-60) reveals mensacarcin’s cytostatic properties in almost all tested cell lines and distinct cytotoxic properties specifically in eight melanoma cell...

Resource Type:

Masters Thesis

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Blakemore, Dr. Jane Ishmael, Dr. Kerry McPhail, Dr. Siva Kolluri and Dr. Taifo Mahmud for their insight
Quantitative determination of emerging contaminants, solvent stabilizers and fullerene nanomaterials, in biological and environmental systems

Creator:

Isaacson, Carl W.

Abstract:

To determine the impact of emerging environmental contaminants on human and environmental health, quantitative analytical methods are required. Analysis of emerging contaminants is hampered by their widely varying physical-chemical properties. Therefore quantitative analytical methods must be developed to determine the behavior of emerging contaminants in environmental systems. A quantitative analytical...

Resource Type:

Dissertation
Innovative Bioanalytical Tools & Methods for Combinatorial Non-Coding RNA Analysis

Creator:

Zhang, Lulu

Abstract:

Recently researchers have discovered that groups of small non-coding RNAs (ncRNAs) play regulatory roles in gene expression and participate in various biological processes. For example, pathogenesis of many diseases, cell cycle regulation, and signaling pathways. Intracellular and live cell imaging of small ncRNA groups will reveal their relative expression levels...

Resource Type:

Dissertation

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Johnson, Dr. Staci Simonich, Dr. Siva Kolluri, Dr. Dipankar Koley, Dr. Christopher Beaudry, and Dr