Studies towards the total synthesis of (+)-Phomactin A (1), D (6), and G (9), fungal metabolites with unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 354 and 356, which contain all of the carbon atoms of 1, 6 and 9....
Lamellar x-ray diffraction was studied from thin films of L-α-1,2-dipalmitoyl lecithin (DPL) and a 1:1 mixture (BrDPL) of L-α-l-palmitoyl-2-(9- bromopaimitoyl) lecithin and its 10-bromo analog. The specimens had high lamellar order, with an upper bound on the mosaicity of 6 mrad (0.4°) for DPL and BrDPL. With various water contents,...
The variegated aqueous chemistries of metal cations are applied to the design and synthesis of non-toxic solution precursors suitable for additive printing of large-area oxide electronics. Polycondensation behaviors of aqueous Al+3 and PO4 +3 are manipulated in the deposition of atomically smooth amorphous aluminum oxide phosphate (AlPO) dielectric films. AlPO...
Early studies on the biosynthesis of the quinoline quinone portion of
streptonigrin, 1, had suggested the intermediacy of novel aromatic amino
acids. In order to test this hypothesis, a series of compounds was synthesized
and tested for potential incorporation. [4-¹⁵N] 4-Aminoanthranilic acid,
4 5 a , [4-² H] 7-aminoquinaldinic acid,...
Automation of computational chemistry, while only an engineering feat, has the potential to accelerating computational research be removing all by the science. The work in this thesis mainly discusses fundamental understanding of complex chemical systems. What is not obvious are the numerous tasks necessary for this fundamental understanding. Under the...
Part 1
The concentration of seventeen elements in two species of fungus
which cause wheat bunt disease, Tilletia caries (DC.)Tul. (TS) and
Tilletia controversa Kiihn (DS), were determined by instrumental neutron
activation analysis in 37 TS spore samples, and 31 DS spore samples.
Aluminum was chosen as a soil contamination...