My work on computing complex catalyzed organic transformations reveals that only a few subtle chemical factors, e.g. non-classical hydrogen bonding, (hyper)conjugation and steric effects, common across different catalyst manifolds are critical for catalysis and selectivity. Rational manipulation and exploitation of these factors has led to improved catalyst designs, which has...
The preparation and characterization of thin film oxides and chalcogenides by pulsed laser deposition (PLD) is presented. An overview of fundamental PLD concepts are presented and are followed by a description implementation and development of the PLD systems at OSU. We present the results of thin film growth of high...
Studies toward the total syntheses of highly potent cytotoxic alkaloids
including the bromopyrrole alkaloids and indole alkaloids were conducted and are
described. Studies carried out in the course of this dissertation consist of five total syntheses of natural products that include bromopyrrole alkaloids nagelamide A, D and agelastatin D as...
Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...
Samarium
(III)
and
promethium
(III)
were
studied
by
chronopotentiometry
in
a
molten
LiCl-KC1
eutectic.
Tungsten
electrodes
were
used
to
avoid
alloying
effects
encountered
with
platinum
electrodes.
Adsorption
phenomena
were
observed
which
prevented
the
study
of
any
kinetic
effects.
The
quarter
wave
potentials
were
measured
as:
Sm(III)
=
0.95
±
0.05...
Direct current conductivity measurements on KC1:O[superscript]= crystals
were used to determine an enthalpy of 0.42 ev for the dissociation for
anion-vacancy-oxide ion complex.
The entropy of dissociation was
found to be approximately -4x 10⁻⁴ev deg⁻¹. The intrinsic "activation" energy was found to be 1.91 ev as compared to 1.95 ev,...
The variegated aqueous chemistries of metal cations are applied to the design and synthesis of non-toxic solution precursors suitable for additive printing of large-area oxide electronics. Polycondensation behaviors of aqueous Al+3 and PO4 +3 are manipulated in the deposition of atomically smooth amorphous aluminum oxide phosphate (AlPO) dielectric films. AlPO...
Optimization of the galvanovoltammetric determination of dissolved
chlorine in a flowing stream was achieved through the use of
an analog computational device and improvements in the design of the
galvanovoltammetric cell and accompanying electronic circuitry. An
analysis system, applicable to industrial use over a range of flow
rates and dissolved...
In this dissertation, I present electronic spectroscopy of a few biologically relevant species and their complexes with solvent molecules in the gas phase using a variety of techniques, including resonantly enhanced multiphoton ionization (REMPI), laser induced fluorescence (LIF), and zero kinetic energy (ZEKE) photoelectron spectroscopy. My work on several methylated...
New transparent p- and n-type semiconductors and luminescent materials have been prepared and characterized. Synthesis, structures, optical and electrical properties of new chalcogenide fluoride p-type transparent semiconductors MCuQF (M=Ba, Sr; Q=S, Se, Te) are described. Band-gap tuning and improvement in conductivity through p-type doping are demonstrated in the family. The...