Index Catalog // ScholarsArchive@OSU

Studies towards the total syntheses of (+)-phomactins A, D and G

Creator:: Schwartz, Keith D.
Abstract:: Studies towards the total synthesis of (+)-Phomactin A (1), D (6), and G (9), fungal metabolites with unique molecular architecture and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 354 and 356, which contain all of the carbon atoms of 1, 6 and 9....
Resource Type:: Dissertation
Full Text:: James D. White Studies towards the total synthesis of (+)-Phomactin A (1), D (6), and G (9), fungal

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Creator:: Shaw, Subrata
Abstract:: This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Resource Type:: Dissertation
Full Text:: [2.2.2]octane: A Novel C2-Symmetric Scaffold for Asymmetric Catalysis Abstract approved: James D

Approaches toward the asymmetric synthesis of pillaromycin A

Creator:: Nolen, Ernest G.
Resource Type:: Dissertation
Full Text:: Ernest G. Nolen Jr. ACKNOWLEDGEMENTS I would like to thank Dr. James D. White for his direction and

Aryl acetylene substituent effects : the synthesis and application of biaryls

Creator:: Naffziger, Michael R.
Abstract:: The work described herein details the synthesis and application of biphenyls that probe the effects of hydrogen, Cl / Br, and methyl substituents on the aryl ring of the terminal acetylenic carbon. From this work, we successfully developed the rapid synthesis of phenyl acetylenes in 3-4 steps from inexpensive commercially...
Resource Type:: Masters Thesis
Full Text:: : Rich G. Carter The work described herein details the synthesis and application of biphenyls

Cyclization of olefinic β-ketoesters. An approach to the synthesis of aplysistatin

Creator:: Skeean, Richard William
Resource Type:: Dissertation
Full Text:: . An Approach to the Synthesis of Aplysistatin Abstract Approved: Redacted for privacy 7/ Dr. James D

Synthesis of marine natural products. part I, Cryptophycins-1, -3, -4, -24, and -29, part II, Polycavernoside A

Creator:: Robarge, Lonnie A.
Resource Type:: Dissertation
Full Text:: A. Abstract approved:, James D. White Part 1: A convergent synthesis of cryptophycins has been

Tandem intramolecular photocycloaddition-retro-Mannich fragmentation as a route to indole and oxindole

Creator:: Li, Yang
Abstract:: Irradiation of a tryptamine linked through its side-chain nitrogen to an alkylidene malonate residue results in an intramolecular [2 + 2] cycloaddition to the indole 2,3-double bond. The resultant cyclobutane undergoes spontaneous retro-Mannich fission to produce a spiro[indoline-3,3-pyrrolenine] with relative configuration defined by the orientation of substituents in the transient...
Resource Type:: Dissertation
Full Text:: approved: James D. White

Studies toward the total synthesis of (+)-providencin

Creator:: Jana, Somnath
Abstract:: Studies toward the total synthesis of (+)-providencin (1), a highly oxygenated cembranoid dipterpene with a unique bicyclo[12.2.0]hexadecane skeleton and pronounced biological activity, are described. These studies resulted in the synthesis of advanced intermediates 320 and 332 which contain all of the carbon atoms of 1. In a first generation approach...
Resource Type:: Dissertation
Full Text:: approved: _____________________________________________________ James D. White Studies toward

Design, characterization, and application of spectrometers for determination of low-level dissolved oxygen with small-volume sampling methodology

Creator:: Cakin, Defne
Abstract:: New analytical methods and instrumentation were developed for the determination of dissolved oxygen (DO) at low concentrations in water. The methods were based on monitoring the absorbance increase due to the oxidation of reduced indigo carmine (IC) by oxygen in the sample in different types of spectrometer cells. Spectrophotometer cells...
Resource Type:: Dissertation
Full Text:: : ___________________________________________ James D. Ingle, Jr. New analytical methods and instrumentation were developed for the

Development of trace enrichment techniques for trace metals in natural waters using high pressure liquid chromatography

Creator:: Ambrose, Arthur Sigurd
Abstract:: An on-line trace enrichment (TE) system, based on high pressure liquid chromatogroaphy (HPLC) and flame atomic absorption (AA), has been developed for trace metal analysis. The sample is pumped through a column filled with a cation exchange resin which traps metal ions. The ions are subsequently stripped from the column...
Resource Type:: Dissertation
Full Text:: Chromatography Abstract approved: Redacted for Privacy James D. Ingle, Jr. An on-line trace enrichment (TE

ScholarsArchive@OSU

Studies towards the total syntheses of (+)-phomactins A, D and G

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Approaches toward the asymmetric synthesis of pillaromycin A

Aryl acetylene substituent effects : the synthesis and application of biaryls

Cyclization of olefinic β-ketoesters. An approach to the synthesis of aplysistatin

Synthesis of marine natural products. part I, Cryptophycins-1, -3, -4, -24, and -29, part II, Polycavernoside A

Tandem intramolecular photocycloaddition-retro-Mannich fragmentation as a route to indole and oxindole

Studies toward the total synthesis of (+)-providencin

Design, characterization, and application of spectrometers for determination of low-level dissolved oxygen with small-volume sampling methodology

Development of trace enrichment techniques for trace metals in natural waters using high pressure liquid chromatography

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Conference Name

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search