Index Catalog // ScholarsArchive@OSU

Increasing Vitamin D Levels to Improve Fertilization Rates in Cattle

Creator:: Peixoto de Souza, Vanessa
Abstract:: Recently, an interest in supplementation of vitamin D to improve aspects of health, especially in human fertility, has emerged. However, supplementation of Vitamin D above the minimum required levels to prevent deficiency has yet to be explored in cattle despite evidence for vitamin D receptors in reproductive tissues. The objective...
Resource Type:: Masters Thesis

Musculoskeletal Injury Pathogenesis in Racehorses

Creator:: Collar, Elizabeth M.
Abstract:: Racehorses are elite athletes that undergo repetitive stresses from jogging, cantering, and galloping exercises, and there is significant evidence that the majority of racehorse musculoskeletal injuries are due to repetitive stress or overuse. Musculoskeletal injuries have negative consequences on the racing industry through the loss of use or death of...
Resource Type:: Dissertation
Full Text:: of veterinary research 2007;68:760-771. 20. Estberg L, Stover SM, Gardner IA, et al. Relationship

Clinical Applications of Lactate Measurements in Equine Veterinary Medicine

Creator:: Baker, Rose E.
Abstract:: Lactate is an end-product of both aerobic and anaerobic glycolysis and it can be used as an energy source for tissues. It is produced by all cells in the mammalian body that can metabolize glucose. Increased production of lactate can be seen with there is an increase in cellular metabolism...
Resource Type:: Masters Thesis
Full Text:: infusion. While lactate did not elevate above the normal threshold value (>2.0 mmol/L), these horses

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Creator:: Nagamine, Brandy S.
Abstract:: The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
Resource Type:: Dissertation
Full Text:: . Liu, S. E. Sharfstein, T. G. Graeber, P. A. Sieling, Y. J. Liu, T. H. Rea, B. R. Bloom, and R. L

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Creator:: Arnold, Holly Kristin
Abstract:: The past decade of research has potentiated a revolution in our understanding of mammalian health and evolution by revealing that the gut microbiome plays a central role in mammalian physiology. Our ability to unlock this potential hinges upon the identification of specific groups of gut microbes that elicit effects on...
Resource Type:: Dissertation
Full Text:: to Dr. Jana Gordon for her support of me as a clinician as well as Dr. Stacie Summers who provided

Harnessing the Potential of Gut Microbiome in the Context of Type 2 Diabetes

Creator:: Gurung, Manoj
Abstract:: Gut microbiota plays an essential role in health and diseases, a fact already established. With the explosive increase in obesity and its main complication, Type 2 Diabetes Mellitus (T2D), there is an immediate need for novel methods of diagnosis, prevention and treatment of these conditions. In the last one and...
Resource Type:: Dissertation
Full Text:: ). 4. George, A. M., Jacob, A. G. & Fogelfeld, L. Lean diabetes mellitus: An emerging entity in the era

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Creator:: Sackinger, Emily P.
Abstract:: Alzheimer’s Disease (AD) is an abnormal part of aging that mainly affects those over the age of 65. The current therapies are only FDA approved for mild to moderate AD symptoms. Cannabidiol (CBD) is a non-intoxicating constituent of Cannabis sativa that has been shown to have beneficial effects on cancer,...
Resource Type:: Masters Thesis

Proteomic Profiles of Circulating Exosomes as Biomarkers for Disease Detection in Canine Osteosarcoma

Creator:: Brady, Jacqueline V.
Abstract:: Osteosarcoma (OSA) is the most common primary skeletal tumor in dogs accounting for 85% of bone tumors and nearly 6% of all canine neoplasms. They are highly aggressive tumors that carry a poor prognosis despite intensive treatment, highlighting the need for more effective diagnostic and therapeutic tools. Recent research in...
Resource Type:: Masters Thesis
Full Text:: ) supplemented with 100 units/mL penicillin, 50 µg/mL streptomycin, and 2 mM L- glutamine with 10% fetal bovine

Characterization of Membrane Vesicles Released by the Opportunistic Human Pathogen Mycobacterium avium subsp. hominissuis (MAH) in Response to an in vitro System Mimicking the Phagosomal Environment

Creator:: Chiplunkar, Sanket S.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) belongs to the most-clinically significant non-tuberculous mycobacterial (NTM) pathogens with constant increase in disease prevalence, mainly in several industrialized western countries where tuberculosis is less prevalent. Upon entry into the alveolar space, MAH is engulfed by resident-macrophages, where the pathogen adapts to the hostile phagosomal...
Resource Type:: Masters Thesis
Full Text:: days, in case of MAH104). Mid-log phase MAH104 cultures were centrifuged at 2000 × g for 20 min, and

Molecular Signaling Patterns of the Articular Cartilage and Marginal Transition Zone in Foals with Osteochondrosis

Creator:: Marchant, Liz
Abstract:: Osteochondrosis (OC) is a developmental orthopedic disease that results from a disruption to normal endochondral ossification in the articular-epiphyseal growth complex. In mammals, the hedgehog pathway and growth factor signaling are essential to this process. Previous studies in yearling horses with OC have shown upregulation of Indian hedgehog and insulin-like...
Resource Type:: Masters Thesis
Full Text:: expression (Gordon and Nusse, 2006). The hedgehog (Hh) pathway has three primary family members

ScholarsArchive@OSU

Increasing Vitamin D Levels to Improve Fertilization Rates in Cattle

Musculoskeletal Injury Pathogenesis in Racehorses

Clinical Applications of Lactate Measurements in Equine Veterinary Medicine

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Harnessing the Potential of Gut Microbiome in the Context of Type 2 Diabetes

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Proteomic Profiles of Circulating Exosomes as Biomarkers for Disease Detection in Canine Osteosarcoma

Characterization of Membrane Vesicles Released by the Opportunistic Human Pathogen Mycobacterium avium subsp. hominissuis (MAH) in Response to an in vitro System Mimicking the Phagosomal Environment

Molecular Signaling Patterns of the Articular Cartilage and Marginal Transition Zone in Foals with Osteochondrosis

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