Index Catalog // ScholarsArchive@OSU

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Creator:: Arnold, Holly Kristin
Abstract:: The past decade of research has potentiated a revolution in our understanding of mammalian health and evolution by revealing that the gut microbiome plays a central role in mammalian physiology. Our ability to unlock this potential hinges upon the identification of specific groups of gut microbes that elicit effects on...
Resource Type:: Dissertation
Full Text:: Thomas J. Sharpton The past decade of research has potentiated a revolution in our understanding

Inotropic and Chronotropic Effects of Sotalol in Healthy Dogs

Creator:: Treseder, Julia R.
Abstract:: Sotalol is a class III anti-arrhythmic drug with class II properties that is commonly used in the treatment of ventricular tachyarrhythmias in dogs. The anti-arrhythmic effects of sotalol are mediated by an increase in action potential duration and prolongation of atrial and ventricular repolarization via antagonism of the delayed rectifier...
Resource Type:: Masters Thesis

Inter- and Intra-rater Reliability and Agreement in Determining Tumor Margins and Inter-surgeon Agreement in Determining 3 cm Surgical Margins of Subcutaneous Tumors in Dogs

Creator:: Ranganathan, Bharadhwaj
Abstract:: Determination of the gross edge of a tumor is required during patient staging, assessing response to therapy, and for planning and executing surgical resection of locally invasive neoplasms. Disagreement in determination of the gross edge of the tumor is likely to directly affect patient staging, assessing response to therapy and...
Resource Type:: Masters Thesis
Full Text:: JM, et al. 2013; Simpson AM, et al. 2004; Dernell WS, et al. 1998; Ehrhart N, 2005). Tumor size is

The Inhibitory Activity of Essential Oil Constituents Against Clostridium perfringens Type A Isolates

Creator:: Alanazi, Saud
Abstract:: C. perfringens type A isolates are the causative agents of C. perfringens type A food poisoning (FP) and non-food-borne (NFB) human gastrointestinal diseases. In this study, we evaluated the antimicrobial effect of essential oil constituents (cinnamaldehyde, eugenol, allyl isothiocyanate (AITC), and carvacrol) against C. perfringens FP and NFB isolates grown...
Resource Type:: Masters Thesis
Full Text:: major lethal toxins (alpha, beta, iota and epsilon) (Raju & Sarker, 2005; Simpson, Stiles, Zepeda

Modeling the Dynamics of Vector–host Interactions in Avian Communities: Eastern Equine Encephalitis Virus as a Model System

Creator:: Muller, Timothy
Abstract:: Understanding the dynamics of seasonal epizootics of vector-borne pathogens infecting multiple host species presents several challenges. The transmission potential of competent hosts depends on factors influencing the contact rate between hosts and vectors. Feeding preferences of vectors can determine which host species drive the prevalence of infection throughout the overall...
Resource Type:: Masters Thesis
Full Text:: /zoonotic-diseases.html 2. Simpson JE, Hurtado PJ, Medlock J, Molaei G, Andreadis TG, Galvani AP, et al

Clinical Applications of Lactate Measurements in Equine Veterinary Medicine

Creator:: Baker, Rose E.
Abstract:: Lactate is an end-product of both aerobic and anaerobic glycolysis and it can be used as an energy source for tissues. It is produced by all cells in the mammalian body that can metabolize glucose. Increased production of lactate can be seen with there is an increase in cellular metabolism...
Resource Type:: Masters Thesis
Full Text:: RD, Simpson R. Lactate metabolism. Anesthesiology. 1975;43(6):661- 673. 3. Lagutchik MS, Ogilvie

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Creator:: Sackinger, Emily P.
Abstract:: Alzheimer’s Disease (AD) is an abnormal part of aging that mainly affects those over the age of 65. The current therapies are only FDA approved for mild to moderate AD symptoms. Cannabidiol (CBD) is a non-intoxicating constituent of Cannabis sativa that has been shown to have beneficial effects on cancer,...
Resource Type:: Masters Thesis
Full Text:: to the environment (J. Canas, Quesada, Antoli, & Fajardo, 2003; J. J. Canas, Fajardo, & Ladislao

Inhibition of Clostridium perfringens spore growth by synergistic effects of different antimicrobials

Creator:: Alhabeeb, Rabiaa
Abstract:: Clostridium perfringens is a spore-forming anaerobic organism that is commonly present in fresh meat and poultry. The organism's spores can survive a range of food processing methods. C. perfringens type F isolates are the causative agents of C. perfringens type F food poisoning (FP) and non-food borne (NFB) human gastrointestinal...
Resource Type:: Masters Thesis
Full Text:: active site and an alpha- sandwich C-terminal domain that is responsible for membrane binding ((J

The immunomodulatory role of canine mesenchymal stem cell-derived extracellular vesicles

Creator:: Phelps, Shannon M.
Abstract:: Immune-mediated diseases are a frequent cause of morbidity and mortality in canine patients. Treatments currently involve generalized suppression of the immune system, and corticosteroids are often used as a first-line agent. While often effective, corticosteroids are unlikely to induce remission without substantial side effects. Second-line immunosuppressive agents may be effective...
Resource Type:: Masters Thesis

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

Creator:: Spagnoli, Sean
Abstract:: Since its inception as a laboratory animal in the early 1970s, the zebrafish has proven itself a rising star in the world of comparative biomedical sciences due to its short generation time, ease of care, external fertilization, and transparent larvae. In a very few decades, the zebrafish has been utilized...
Resource Type:: Dissertation
Full Text:: . 7 1.6 References Grunwald D and Eisen J. Headwaters of the zebrafish—emergence of a

ScholarsArchive@OSU

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Inotropic and Chronotropic Effects of Sotalol in Healthy Dogs

Inter- and Intra-rater Reliability and Agreement in Determining Tumor Margins and Inter-surgeon Agreement in Determining 3 cm Surgical Margins of Subcutaneous Tumors in Dogs

The Inhibitory Activity of Essential Oil Constituents Against Clostridium perfringens Type A Isolates

Modeling the Dynamics of Vector–host Interactions in Avian Communities: Eastern Equine Encephalitis Virus as a Model System

Clinical Applications of Lactate Measurements in Equine Veterinary Medicine

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Inhibition of Clostridium perfringens spore growth by synergistic effects of different antimicrobials

The immunomodulatory role of canine mesenchymal stem cell-derived extracellular vesicles

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

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