Index Catalog // ScholarsArchive@OSU

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Creator:: Sackinger, Emily P.
Abstract:: Alzheimer’s Disease (AD) is an abnormal part of aging that mainly affects those over the age of 65. The current therapies are only FDA approved for mild to moderate AD symptoms. Cannabidiol (CBD) is a non-intoxicating constituent of Cannabis sativa that has been shown to have beneficial effects on cancer,...
Resource Type:: Masters Thesis

Effect of Audible Static on Blood Pressure Measurement by Doppler Ultrasound Sphygmomanometry in Cats

Creator:: Uematsu, Sayaka
Abstract:: Systemic hypertension, a persistent elevation in systemic arterial blood pressure (BP), is a well-recognized disorder in cats. Failing to diagnose it accurately could lead to organ damage or unnecessary lifelong therapy. Doppler ultrasonic flow detectors are commonly used for indirect BP measurements in cats. However, whether the audible static from...
Resource Type:: Masters Thesis

Walrus Vibrissae: Determining Growth Rate, Indication of Niche Variability, and Implications for Climate Resiliency

Creator:: Blackfield, Danielle
Abstract:: Pacific walrus (Odobenus rosmarus) are particularly vulnerable to the impacts of climate change due to the high reliance on sea ice for safety, transport, and social behaviors. Additionally, the walrus diet consists of predominantly bivalves, whose populations are in decline as a result of ocean acidification. We first determined the...
Resource Type:: Masters Thesis

The immunomodulatory role of canine mesenchymal stem cell-derived extracellular vesicles

Creator:: Phelps, Shannon M.
Abstract:: Immune-mediated diseases are a frequent cause of morbidity and mortality in canine patients. Treatments currently involve generalized suppression of the immune system, and corticosteroids are often used as a first-line agent. While often effective, corticosteroids are unlikely to induce remission without substantial side effects. Second-line immunosuppressive agents may be effective...
Resource Type:: Masters Thesis

Death Investigation: Factors Associated with Scene Investigation and Autopsy Completion at Two US Medicolegal Offices

Creator:: Snippen, Jennifer R.
Abstract:: Background/Purpose: US public health, criminal justice, and many other social and scientific processes are affected by the quality of data obtained about death. Yet, little research has focused on how death investigations are conducted. The overall goal of this research was to examine the process by which information was obtained...
Resource Type:: Dissertation

Molecular Signaling Patterns of the Articular Cartilage and Marginal Transition Zone in Foals with Osteochondrosis

Creator:: Marchant, Liz
Abstract:: Osteochondrosis (OC) is a developmental orthopedic disease that results from a disruption to normal endochondral ossification in the articular-epiphyseal growth complex. In mammals, the hedgehog pathway and growth factor signaling are essential to this process. Previous studies in yearling horses with OC have shown upregulation of Indian hedgehog and insulin-like...
Resource Type:: Masters Thesis

Assessing Mercury Levels, Health Metrics, and Immune Function in Non-stranded Male California and Steller Sea Lions in Oregon

Creator:: Rae, Samantha N.
Abstract:: California and Steller sea lions (Zalophus californianus, Eumetopias jubatus, respectively) are considered sentinel species because they have long life spans, are long-term coastal residents, feed at high trophic levels, and have large blubber stores that serve as depots for anthropogenic toxicants. There are few studies on sea lion health and...
Resource Type:: Masters Thesis

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Creator:: Nagamine, Brandy S.
Abstract:: The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
Resource Type:: Dissertation

Identification of Mycobacterium smegmatis Surface Proteins for Stimulation of Anti-Mycobacterial Killing Activity of Macrophages

Creator:: Islam, Sabrina
Abstract:: Mycobacterium avium subspecies hominissuis (M. avium) is a ubiquitous, acid-fast organism found in water and soil. This opportunistic pathogen is a common causative of pulmonary diseases in immunocompromised individuals and prevalent infection in HIV/AIDS patients. As a primary defense response against infection, immune cells such as macrophages phagocytize M. avium...
Resource Type:: Masters Thesis

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Creator:: Arnold, Holly Kristin
Abstract:: The past decade of research has potentiated a revolution in our understanding of mammalian health and evolution by revealing that the gut microbiome plays a central role in mammalian physiology. Our ability to unlock this potential hinges upon the identification of specific groups of gut microbes that elicit effects on...
Resource Type:: Dissertation

ScholarsArchive@OSU

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Effect of Audible Static on Blood Pressure Measurement by Doppler Ultrasound Sphygmomanometry in Cats

Walrus Vibrissae: Determining Growth Rate, Indication of Niche Variability, and Implications for Climate Resiliency

The immunomodulatory role of canine mesenchymal stem cell-derived extracellular vesicles

Death Investigation: Factors Associated with Scene Investigation and Autopsy Completion at Two US Medicolegal Offices

Molecular Signaling Patterns of the Articular Cartilage and Marginal Transition Zone in Foals with Osteochondrosis

Assessing Mercury Levels, Health Metrics, and Immune Function in Non-stranded Male California and Steller Sea Lions in Oregon

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Identification of Mycobacterium smegmatis Surface Proteins for Stimulation of Anti-Mycobacterial Killing Activity of Macrophages

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

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