Index Catalog // ScholarsArchive@OSU

The Effect of Non-Steroidal Anti-Inflammatory Drugs on Canine Transitional Cell Carcinoma and Its Correlation with Cyclooxygenase-2 Expression

Creator:: Weinman, Marcus Andrew
Abstract:: Canine transitional cell carcinoma (TCC) has been shown to have a substantial inflammatory component. It exhibits genotypic and morphologic elements that resemble its human counterpart. Cyclooxygenases (COX) are key enzymes in the synthesis of proinflammatory molecules, such as prostaglandins. Excess prostaglandin production through cyclooxygenases may promote oncogenesis and progression of...
Resource Type:: Honors College Thesis
Full Text:: requirements for the degree of Honors Baccalaureate of Science in Microbiology (Honors Scholar

Linking phylogenetic identity and biogeochemical function of uncultivated marine microbes with novel mass spectrometry techniques

Creator:: Bryson, Samuel J.
Abstract:: The combined activities of diverse heterotrophic marine microorganisms significantly shape global biogeochemical cycles, but models of these activities are currently limited to aggregate microbial community processes, and it remains unclear how community structure and the functional roles of specific microbial taxa should be integrated into these models. Therefore, understanding the...
Resource Type:: Dissertation
Full Text:: ................................................................................................................. 115 4.4.6 Activity measures correlate with proteome heterogeneity and nutritional requirements

How Do Parasites Infect Salmon? Comparative Transcriptomics Reveal Myxozoan Adaptations for Parasitism

Creator:: Americus, Benjamin
Abstract:: The phylum Cnidaria contains three main branches: Anthozoa (corals, sea anemones) Medusozoa (jellyfish, hydra), and Endocnidozoa. This latter branch is characterized by parasitism and contains the microscopic fish-parasites Myxozoa. Myxozoa are highly simplified, consisting of only a few cell types, however they have retained the nematocyst stinging cells and complex...
Resource Type:: Dissertation
Full Text:: Quantitative Life Science and Aquatic Animal Health Lab, principally Chris Sullivan and Ruth Milston-Clements

The broad spectrum antiviral compound ST-669 affects vesicular trafficking in Chlamydia-infected cells

Creator:: Valiant, William G.
Abstract:: Our laboratory is exploring the mechanism of action of a novel broad spectrum antiviral, ST-669. This compound has activity against a variety of different viruses and the obligate intracellular bacterium, Chlamydia. In this study, we explored the effects of ST-669 when the cell cycle of the host cells was altered....
Resource Type:: Honors College Thesis
Full Text:: Baccalaureate of Science Microbiology (Honors Scholar) Presented May 13, 2015 Commencement June

The Influence of Microbial Communities on Spatiotemporal Elemental Cycling in Coastal Margins Revealed by Community- and Population-level Genomics and Proteomics

Creator:: Kieft, Brandon P.
Abstract:: Biotic and abiotic processes at continent-ocean interfaces cycle a disproportionate mass of carbon and nutrients relative to their global surface area, and microbial activity is a principal determinant of organic and inorganic matter flux in these transition zones. Most studies using modern high-throughput ‘omics techniques to link microorganisms with costal...
Resource Type:: Dissertation
Full Text:: Science Foundation (EAPSI), the OSU Graduate School (Travel Award, Provost’s Award), and the Department

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

Creator:: Lewis, Matthew S.
Abstract:: Mycobacterium avium subspecies hominissuis (MAH) is an opportunistic pathogen that is ubiquitous in the environment and often isolated from faucets and showerheads. MAH mostly infects humans with an underlying disease, such as chronic pulmonary disorder (COPD), cystic fibrosis (CF), or are immunocompromised, though infections in patients without concurrent disease are...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Matthew S. Lewis for the degree of Master of Science in Microbiology

A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

Creator:: Mellbye, Brett L.
Abstract:: High-throughput culturing (HTC) consisting of extinction culturing in autoclaved seawater has led to the isolation and characterization of many novel strains of oligotrophic marine bacteria. Strain HTCC 2207 was isolated from the Oregon coast by the HTC method. Phylogenetic analysis based on 16S rRNA gene sequence showed that this strain...
Resource Type:: Honors College Thesis
Full Text:: THESIS OF Brett L. Mellbye for the degree of Honors Baccalaureate of Science in Microbiology presented

Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

Creator:: Everman, Jamie L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne's disease, a chronic inflammatory bowel disease that affects ruminant populations worldwide. The characteristic stages of the disease make diagnosis difficult, resulting in silent transmission among animals in a herd for years before proper detection of the infection. The extensive...
Resource Type:: Dissertation

Further Understanding Mycobacterial Biofilms and Their Interaction with the Host

Creator:: Rose, Sasha J.
Abstract:: Respiratory infections caused by nontuberculous mycobacteria (NTM), especially Mycobacterium avium, can lead to progressive, recurrent disease that is refractory to therapy. Bacterial biofilms are intrinsically resistant to a variety of stressors and pressures, including host killing mechanisms and antibiotic therapy. Though it is becoming increasingly evident that NTM biofilms are...
Resource Type:: Dissertation
Full Text:: of science and not just the technical skills, which I believe is very important to produce a well

Photosynthetic Energy Allocation Strategies of Thalassiosira pseudonana During Light Limited Growth

Creator:: Fisher, Nerissa L.
Abstract:: Photosynthetic energy allocation strategies were investigated in the marine diatom, Thalassiosira pseudonana, grown under a wide range of light limitation. Steady-state, continuous cultures were established at three light-limited growth rates. Simultaneous measurements of photosynthetic activity were made that targeted different points in photosynthetic energy flow from gross to net photosynthesis....
Resource Type:: Masters Thesis
Full Text:: Nerissa L. Fisher for the degree of Master of Science in Microbiology presented on June 10, 2015

ScholarsArchive@OSU

The Effect of Non-Steroidal Anti-Inflammatory Drugs on Canine Transitional Cell Carcinoma and Its Correlation with Cyclooxygenase-2 Expression

Linking phylogenetic identity and biogeochemical function of uncultivated marine microbes with novel mass spectrometry techniques

How Do Parasites Infect Salmon? Comparative Transcriptomics Reveal Myxozoan Adaptations for Parasitism

The broad spectrum antiviral compound ST-669 affects vesicular trafficking in Chlamydia-infected cells

The Influence of Microbial Communities on Spatiotemporal Elemental Cycling in Coastal Margins Revealed by Community- and Population-level Genomics and Proteomics

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

Disease models and infectious phenotypes of Mycobacterium avium subspecies paratuberculosis

Further Understanding Mycobacterial Biofilms and Their Interaction with the Host

Photosynthetic Energy Allocation Strategies of Thalassiosira pseudonana During Light Limited Growth

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