Index Catalog // ScholarsArchive@OSU

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:: Alzhanov, Damir T.
Abstract:: The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
Resource Type:: Dissertation
Full Text:: Daniel D. Rockey The majority of our modern understanding of bacterial pathogenesis is

Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Creator:: Chiu, Wei-Wei
Abstract:: In this thesis, I studied the translation of dengue virus RNA using a luciferase reporter gene system in Vero cells. The dengue reporter mRNA construct, which harbors 5´-terminal viral nts and 3´-terminal nts, could be translated efficiently compared to an alpha globin reporter construct. The 5´-cap structure and 3´-untranslated region...
Resource Type:: Dissertation
Full Text:: collection in all the electroporation experiments and the critical reading. Dr. Richard M. Kinney

Molecular basis for Clostridium perfringens spore resistance to heat and other environmental stress factors

Creator:: Raju, Deepa
Abstract:: Clostridium perfringens type A isolates producing enterotoxin (CPE) are an important cause of both food poisoning (FP) and non food borne gastrointestinal diseases (NFBGID) in both humans and animals. C. perfringens type A food poisoning is caused by isolates carrying the CPE encoding gene (cpe) on the chromosome while the...
Resource Type:: Dissertation
Full Text:: , Daniel Paredes-Sabja, Nahid Mahfuz, Mike Waters, Ben Harrison and all the other members of the Sarker

Survival and persistence of Bacteroidales human and ruminant specific fecal markers and occurrence with fecal pathogens

Creator:: Walters, Sarah P.
Abstract:: Aquatic fecal contamination from non-point sources impairs environmental health and serves as a vehicle for transmission of waterborne disease, resulting in economic losses worldwide. Accurate methods of diagnosing fecal pollution and its source are needed to prevent human exposure, remediate pollution, and reduce economic impacts. In order to obtain this...
Resource Type:: Dissertation
Full Text:: graduate committee, Drs. Daniel J. Arp, Peter J. Bottomley, Evelyn B. Sherr, and Susan J. Tornquist

Characterization of vaccinia virus A12L protein : its proteolysis and functional analyses in virus replication

Creator:: Yang, Su Jung
Abstract:: In order to produce infectious virus progeny, vaccinia virus (VV) undergoes morphogenic proteolysis to regulate the structural rearrangements of virus particles. Several of the major structural precursor proteins of VV are cleaved at a conserved Ala-Gly-X (where X is any amino acid) motif by the VV I7L core protein proteinase...
Resource Type:: Dissertation
Full Text:: all the committee members, Dr. Daniel Rockey, Dr. Theo Dreher, Dr. Thomas Wolpert, Dr. Machteld

Analysis of chlamydial and host proteins associated with infection

Creator:: Chu, Hencelyn
Abstract:: Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal host processes. Within host cells, their developmental cycle takes place inside non-acidified vacuoles termed inclusions. An inclusion membrane composed primarily of secreted chlamydial synthesized proteins called Incs encloses the inclusion. At this location, Incs have...
Resource Type:: Dissertation
Full Text:: Abstract approved: _____________________________________________________ Daniel D. Rockey

Clostridium perfringens sporulation and gliding motility

Creator:: Huang, I-Hsiu
Abstract:: Clostridium perfringens type A isolates, an anaerobic enterotoxigenic spore forming bacterium, are the third leading cause of food-borne disease in the United States. Factors that contribute to the virulence of C. perfringens include the ability of the bacterium to form heat resistant spores and to produce an enterotoxin (CPE). Although...
Resource Type:: Dissertation
Full Text:: Sciences. Special thanks to Deepa Raju, Daniel Paredes-Sabja, Mike Waters, Ben Harrison, Nahid Mahfuz

Control of alkane monooxygenase activity and expression in Pseudomonas butanovora

Creator:: Doughty, David M.
Abstract:: The regulation of monooxygenase enzymes has been demonstrated in bacteria that grow on methane and long chain-length alkanes (>C10). Less is known about monooxygenase regulation in short chain alkane oxidizing bacteria that grow on intermediate chain-length alkanes C2-C10. This dissertation focuses on the regulation of butane monooxygenase (BMO) expression and...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF David M. Doughty

An investigation of carbon and nitrogen metabolism through a genomic analysis of the genus Nitrobacter

Creator:: Starkenburg, Shawn R.
Abstract:: The chemolithoautotrophic nitrite oxidizing bacteria (NOB) participate in the biogeochemical cycling of nitrogen by catalyzing and conserving energy from the oxidation of nitrite (NO₂-) to nitrate (NO₃-) via a nitrite oxidoreductase (NXR). The main objective of this work was to comparatively annotate and analyze the genome sequences of Nitrobacter winogradskyi...
Resource Type:: Dissertation
Full Text:: Metabolism’ and manuscript preparation in Chapter 3. Daniel J. Arp contributed to manuscript preparation of

Molecular markers from fecal anaerobes to identify nonpoint source pollution in coastal waters

Creator:: Bernhard, Anne E.
Resource Type:: Dissertation
Full Text:: -limited freshwaters (Daniel et al. 1998). Additionally, allochthonous material from nonpoint sources can

ScholarsArchive@OSU

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Translation of dengue virus RNA : influence of the untranslated regions on 5´-cap dependent translation and ribosome scanning

Molecular basis for Clostridium perfringens spore resistance to heat and other environmental stress factors

Survival and persistence of Bacteroidales human and ruminant specific fecal markers and occurrence with fecal pathogens

Characterization of vaccinia virus A12L protein : its proteolysis and functional analyses in virus replication

Analysis of chlamydial and host proteins associated with infection

Clostridium perfringens sporulation and gliding motility

Control of alkane monooxygenase activity and expression in Pseudomonas butanovora

An investigation of carbon and nitrogen metabolism through a genomic analysis of the genus Nitrobacter

Molecular markers from fecal anaerobes to identify nonpoint source pollution in coastal waters

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