Mycobacterium avium is an intracellular pathogen that is associated with disseminated
infection, especially in patients with acquired immunodeficiency syndrome (AIDS). It
appears that patients with AIDS acquire M. avium mostly through the intestinal tract,
and that bacteria enter the intestinal wall at the terminal ileum. Previous studies have
found that...
Biological agents and their products commonly cause foodborne illnesses. In the United States it is estimated that there are over 76 million cases of foodborne illnesses each year, resulting in an economic loss of approximately $40 billion. These high figures demonstrate the need for bioassays that display a rapid and...
Streptococcus gordonii is a bacterial species that naturally colonizes the oral cavity of most healthy humans. It resides in the mouth as an adherent to dental surfaces and, with few exceptions, does not cause disease in individuals it inhabits. It possesses qualities that encourage its use as a vector to...
Ceratomyxa shasta is a myxozoan parasite of salmonids and requires the freshwater polychaete, Manayunkia speciosa to complete its life cycle. The parasite’s distribution is currently limited to the Pacific Northwest region of North America and has been reported to cause substantial losses of both wild and hatchery salmonids. The spatial...
Science is difficult for even its researchers to understand. Science journalists must understand scientific discoveries well enough to write clear, accurate explanations of scientific discoveries for laypeople. A sense of ethical judgment will help journalists ensure that their accounts are reliable and appropriate. Responsible science journalists will maintain a working...
High-throughput culturing (HTC) consisting of extinction culturing in autoclaved seawater has led to the isolation and characterization of many novel strains of oligotrophic marine bacteria. Strain HTCC 2207 was isolated from the Oregon coast by the HTC method. Phylogenetic analysis based on 16S rRNA gene sequence showed that this strain...
The Chlamydiaceae are a family of obligate intracellular bacteria with a unique biphasic developmental cycle. The replicating, metabolically active, intracellular phase bacteria (RBs) grow within a cellular vacuole know as the inclusion. Since the proteins the Chlamydiaceae secrete into this membrane are the means of host/parasite interaction, they have long...
In the fall of 2005, I studied abroad in Athens, Greece for one term. This is retelling of experiences that I had, written in the style of my memories. While I was in Greece, I kept an electronic diary, a picture diary, and a scrapbook to keep my memories vivid...
Fire blight is a serious disease of apple and pear trees caused by the bacterium, Erwinia amylovora. This bacterium harbors a pathogenesis mechanism known as the Hrp secretory operon which induces some resistance genes and suppresses other resistance genes in the host plant following invasion. While previous researchers analyzed expression...
The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...