Index Catalog // ScholarsArchive@OSU

Secreted Agrobacterium rhizogenes Effector Protein GALLS Interacts with Arabidopsis Host Proteins and Stimulates Agrobacterium-mediated Transformation

Creator:: Wei, Wei
Abstract:: Agrobacterium species transform plant cells by targeting a portion of plasmid-encoded bacterial DNA to the host nucleus. Genetic transformation by A. tumefaciens and A. rhizogenes requires secreted effector proteins. The tumor-inducing (Ti) plasmid from virulent A. tumefaciens encodes VirE2, a secreted single-stranded DNA-binding protein required for efficient transformation of hosts....
Resource Type:: Dissertation
Full Text:: Doctor of Philosophy in Microbiology presented on June 12, 2018. Title: Secreted Agrobacterium

Biology of a constitutively-expressed vaccinia virus gene required for DNA replication

Creator:: Roseman, Nancy A.
Abstract:: Replication of vaccinia virus in the cytoplasm of the infected cell occurs under the direction of virally encoded gene products. Expression of approximately 200 viral genes follows a highly regulated temporal scheme which can be followed biochemically and morphologically during the assembly process. In order to dissect this complex genetic...
Resource Type:: Dissertation
Full Text:: Doctor of Philosophy in Microbiology presented on April 8, 1987 Title: Biology of a Constitutively

The conserved biology of herpesvirus latency : a study in cyprinid herpesvirus 3

Creator:: Reed, Aimee N.
Abstract:: Cyprinid herpesvirus 3 (CyHV-3), commonly known as koi herpesvirus (KHV), is a member of the Alloherpesviridae and is a deadly pathogen for koi and common carp, Cyprinus carpio. It causes severe gill necrosis and nephritis, dermal ulceration and hemorrhage, and mass mortality of up to 100% of affected fish. Fish...
Resource Type:: Dissertation
Full Text:: The Conserved Biology of Herpesvirus Latency: A Study in

Fecal Bacteroidetes host distributions and environmental source tracking

Creator:: Dick, Linda K.
Abstract:: Contamination of recreational and shellfish waters with fecal pollution is a major water quality issue with associated economic impacts and human health risks. Reliable fecal source identification and rapid, quantitative analyses are essential components of risk assessment. Enteric bacteria that are endemic to specific hosts have a potential role as...
Resource Type:: Dissertation
Full Text:: of Doctor of Philosophy in Microbiology presented on November 16, 2004. Title: Fecal Bacteroidetes

Molecular markers from fecal anaerobes to identify nonpoint source pollution in coastal waters

Creator:: Bernhard, Anne E.
Resource Type:: Dissertation
Full Text:: degree of Doctor of Philosophy in Microbiology presented on July 28, 2000. Title: Molecular Markers from

Bacterial Predation in Host Microbiomes

Creator:: Welsh, Rory M.
Abstract:: In host-associated microbiomes, the mechanisms that regulate community composition or the principles that govern dynamics remain far from clear. However, understanding how the structure of microbial communities shift as the system moves away from a healthy state is critical to assessing disease progression and to formulate any potential mitigation strategy....
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Rory M. Welsh for the degree of Doctor of Philosophy in

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:: Alzhanov, Damir T.
Abstract:: The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Damir T. Alzhanov for the degree of Doctor of Philosophy in Microbiology presented on

Chlamydiae under stress : environmental conditions influence the production and localization of chlamydial antigens

Creator:: Brown, Wendy J.
Abstract:: Chlamydiae are obligate intracellular pathogens that cause several serious conditions within the human host. Many of the symptoms associated with infection are thought to stem from the development of aberrant, or persistent, chlamydiae. Factors leading to chlamydial persistence include deprivation of amino acids, the release of certain cellular factors, or...
Resource Type:: Dissertation
Full Text:: Doctor of Philosophy in Microbiology presented on June 28, 2002. Title: Chlamydiae Under Stress

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

Creator:: Ramaswamy, Aishwarya V.
Abstract:: Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
Resource Type:: Dissertation
Full Text:: the degree of Doctor of Philosophy in Microbiology presented on June 02, 2005. Title: Cloning and

A Historical Reflection of Cultural Factors Inhibiting American Healthcare Reform

Creator:: Leathers, James S.
Abstract:: Past healthcare reform has been blinded by the presence of competing philosophies and ideologies that ultimately yielded ineffective compromises or short-terms solutions. With the ever-shifting political and economic landscapes, the future of our nation’s healthcare is in great peril. This paper is a meta-analysis on obstructions to healthcare reform that...
Resource Type:: Honors College Thesis

R factor transfer among bacteria isolated from the environment

Creator:: Latimer, Joan Marie
Resource Type:: Masters Thesis
Full Text:: E. coli biotypes, and one R factor, (Tc, Amp), showed predominance in some samples taken

Harnessing Heterogeneity in Human Gut Microbiome Data

Creator:: Tataru, Christine
Abstract:: The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Resource Type:: Dissertation
Full Text:: for the degree of Doctor of Philosophy in Microbiology presented on December 2, 2022. Title

How Do Parasites Infect Salmon? Comparative Transcriptomics Reveal Myxozoan Adaptations for Parasitism

Creator:: Americus, Benjamin
Abstract:: The phylum Cnidaria contains three main branches: Anthozoa (corals, sea anemones) Medusozoa (jellyfish, hydra), and Endocnidozoa. This latter branch is characterized by parasitism and contains the microscopic fish-parasites Myxozoa. Myxozoa are highly simplified, consisting of only a few cell types, however they have retained the nematocyst stinging cells and complex...
Resource Type:: Dissertation
Full Text:: Benjamin Americus for the degree of Doctor of Philosophy in Microbiology presented on May 23, 2023

Identification of an aerotaxis transducer in Vibrio cholerae

Creator:: Boin, Markus A.
Abstract:: The ability to move towards favorable environmental conditions, called chemotaxis, is common among motile bacteria. In particular aerotaxis has been extensively studied in Escherichia coli. Three putative aer gene homologs were identified in the V. cholerae genome designated VCAer-1 (VC0512) VCAer-2 (VCA0658), and VCAer-3 (VCA0988). Deletion analyses indicated that only...
Resource Type:: Masters Thesis
Full Text:: particularly aerotaxis in the biology of V. cholerae, including its environmental and infectious life stages

The metabolism of 5'-deoxy-5'-methylthioadenosine in Saccharomyces cerevisiae

Creator:: Marchitto, Kevin Scott
Resource Type:: Dissertation
Full Text:: Philosophy in Microbiology presented on April 20, 1982 Title: THE METABOLISM OF 5'-DEOXY-5

The effect and metabolism of 5'-methylthioadenosine in normal and 5'-methylthioadenosine phosphorylase deficient mammalian cells

Creator:: White, Michael William
Resource Type:: Dissertation
Full Text:: Michael W. White for the degree of Doctor of Philosophy in Microbiology presented on October 24, 1983

Transcriptional regulation of Rhizobium meliloti nitrogen fixation genes

Creator:: Evans, Paul D.
Abstract:: The transcriptional promoter sequences for the Rhizobium meliloti nitrogen fixation genes nifA and nifB were cloned to a β-galactosidase gene fusion plasmid vector and transferred by homologous recombination to a specialized transducing phage. The promoter fusions were then transduced to a recombination deficient strain of Escherichia coli as single-copy lysogens...
Resource Type:: Dissertation
Full Text:: Philosophy in Microbiology presented on June 13. 1990. Title: Transcriptional Regulation of Rhizobium

Genetic and biochemical studies in the genus Bacillus

Creator:: Beaty, Jon Stuart
Resource Type:: Dissertation
Full Text:: ABSTRACT OF THE THESIS OF Jon Stuart Beaty for the degree of Doctor of Philosophy in Micro- biology

Assessing disease impacts of hatcheries on downstream salmonids in the Willamette River Basin, Oregon

Creator:: Jakaitis, Michelle
Abstract:: Hatcheries are often perceived as a source of pathogen amplification, potentially increasing disease risk to free-ranging populations; at the same time, free-ranging fishes may introduce pathogens into hatcheries through untreated water sources. Many pathogens exist naturally within the environment (with the exception of introduced pathogens) and the presence of a...
Resource Type:: Masters Thesis
Full Text:: some mitigating strategies. Reviews in Fish Biology and Fisheries 19(1):9– 31. Krkošek, M., M. A

Preventing crown gall disease using oncogene silencing or VirE1-expressing transgenics

Creator:: Humann, Jodi L.
Abstract:: Crown gall disease is caused by the ubiquitous soil bacterium Agrobacterium tumefaciens which transfers a portion if DNA (T-DNA) into the plant cell. Preventing infection by using the biocontrol strain Agrobacterium radiobacter K84 is currently the only defense for crown gall. Two different resistance strategies were examined in this work....
Resource Type:: Dissertation
Full Text:: degree of Doctor of Philosophy in Microbiology presented on August 17. 2005. Title: Preventing Crown Gall

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