Index Catalog // ScholarsArchive@OSU

Molecular basis for Clostridium perfringens spore resistance to heat and other environmental stress factors

Creator:: Raju, Deepa
Abstract:: Clostridium perfringens type A isolates producing enterotoxin (CPE) are an important cause of both food poisoning (FP) and non food borne gastrointestinal diseases (NFBGID) in both humans and animals. C. perfringens type A food poisoning is caused by isolates carrying the CPE encoding gene (cpe) on the chromosome while the...
Resource Type:: Dissertation
Full Text:: I understand that my thesis will become part of the permanent collection of Oregon State

Establishment and dynamics of methane-oxidizing microbial communities in marine sediments

Creator:: Klasek, Scott A.
Abstract:: Marine sediments are vast sources and reservoirs of methane, a potent greenhouse gas. Most of this methane is anaerobically oxidized by archaea before it can reach the overlying ocean, though the efficiency of this process often depends on methane fluxes and mechanisms of fluid transport. Anaerobic methanotrophic archaea, or ANME,...
Resource Type:: Dissertation
Full Text:: Head of the Department of Microbiology Dean of the Graduate School I

Harnessing Heterogeneity in Human Gut Microbiome Data

Creator:: Tataru, Christine
Abstract:: The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
Resource Type:: Dissertation
Full Text:: interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and

Expanding Diagnostic Assays for Pseudoloma neurophilia & Description of the Progression of Infection in Adult Zebrafish Populations

Creator:: Schuster, Corbin J.
Abstract:: Pseudoloma neurophilia is the most common pathogen reported in zebrafish (Danio rerio) research facilities and is an important threat to the zebrafish model. This microsporidian parasite can cause clinical disease, but more importantly is a causative agent of non-protocol induced variation in research. Studies utilizing infected zebrafish, could potentially confound...
Resource Type:: Dissertation
Full Text:: portion of a given population for accurate estimates of prevalence. Thus, I optimized nonlethal assays

What is killing the corals? Viral and bacterial interrogations using metagenomics and microscopy

Creator:: Soffer, Nitzan
Abstract:: Corals have multiple roles in maintaining ocean health and are some of the world’s most diverse ecosystems. The coral animal is host to a multitude of taxa, including symbiotic dinoflagellate algae, fungi, bacteria, protists, and viruses. Environmental stressors and disease agents can perturb the delicate balance of the coral host...
Resource Type:: Dissertation
Full Text:: Growth Anomalies (GAs). First, I set to determine whether viruses may be involved in WP disease from

Comparative genomics of Vibrio and characterizing microbial communities at a shellfish hatchery

Creator:: Delgado, Hanna
Abstract:: Vibrio bacteria are commonly found in freshwater, marine, and estuarine environments. Members of this genus can exist in commensal relationships with marine animals or as planktonic bacteria, however, they are well known for their roles as pathogens towards humans and animals. In this dissertation, I investigated aspects of host-bacteria relationships...
Resource Type:: Dissertation
Full Text:: . In this dissertation, I investigated aspects of host-bacteria relationships with an emphasis on

Controlling Important Pathogens in Zebrafish (Danio rerio) : Assessing Cryopreservation Survival of Bacteria and Parasites and Clinical Sensitivity of Mycobacterial qPCR Assays

Creator:: Norris, Lauren J.
Abstract:: Zebrafish (Danio rerio) are one of the most commonly used animal models in biomedical research. Zebrafish resource facilities, like the Zebrafish International Resource Center (ZIRC) in Eugene, Oregon, are the main providers and keepers of numerous zebrafish wild-type, mutant, and transgenic lines. Although ZIRC maintains live zebrafish at various life...
Resource Type:: Masters Thesis
Full Text:: ). I assessed the survival of two strains of Mycobacterium chelonae (H1E1 and H1E2), one strain of

Chemical and Genetic Investigations of Toxic Freshwater Cyanobacterial Blooms for Improved Monitoring and Understanding of Lake Ecology

Creator:: Collart, Lindsay P.
Abstract:: Toxin production by cyanobacterial harmful algal blooms (cyanoHABs) in freshwater systems has lasting ecological and human impacts. Nutrients, light availability, hydrology, and microbial community composition impact the frequency and intensity of toxic cyanoHABs. Climate change will exacerbate toxic cyanoHABs, making real time and predictive monitoring a vital tool for managing...
Resource Type:: Dissertation
Full Text:: . I studied a cattle toxicosis event in which, unexpectedly, Anabaena/Dolichospermum spp. was the

Genome-enabled investigation of the minimal growth requirements andphosphate metabolism for Pelagibacter marine bacteria

Creator:: Carini, Paul J.
Abstract:: Members of the SAR11 clade of heterotrophic α-proteobacteria are ubiquitous and abundant in the world's oceans where they are thought to play a pivotal role in the global carbon cycle. The first SAR11 bacterium cultivated in vitro, 'Candidatus Pelagibacter ubique' HTCC1062 (Ca. P. ubique), was isolated by dilution into sterile...
Resource Type:: Dissertation
Full Text:: School I understand that my dissertation will become part of the permanent collection of Oregon

New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

Creator:: Banawas, Saeed S.
Abstract:: C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
Resource Type:: Dissertation
Full Text:: findings: (i) Spores of gerKC mutant did not germinate with KCl, L-asparagine, a mixture of asparagine

Characterization of Sporulation and Germination Genes in Clostridium perfringens

Creator:: Talukdar, Prabhat Kumar
Abstract:: Clostridium perfringens is a Gram-positive, anaerobic, spore-forming bacterium that can produce as many as 17 different toxins and are responsible to cause a wide array of gastrointestinal (GI) and histotoxic diseases in humans and animals. As individual strains produce a subset of these toxins, C. perfringens strains can be classified...
Resource Type:: Dissertation
Full Text:: . perfringens possesses several unique characteristics; i) this bacterium is anaerobic and can survive in

Volumetric-modulated arc radiotherapy for pancreatic malignancies : Dosimetric comparison with helical TomoTherapy

Creator:: Ognjenovic, Sanja
Abstract:: Purpose: To compare target dose conformality and OAR sparing afforded by VMAT and HT for pancreatic cancer. Materials and Methods: A retrospective planning study was performed in 18 patients. Total treatment dose was 59.4Gy. OAR and PTV mean doses, conformity indices, isodose volumes, and integral doses were compared. The relationship...
Resource Type:: Honors College Thesis
Full Text:: Honors College I understand that my project will become part of the permanent

The MAV_4644 dual-function channel protein with putative ADP-ribosyltransferase activity of Mycobacterium avium is required for virulence within host macrophages

Creator:: Lewis, Matthew S.
Abstract:: Mycobacterium avium subspecies hominissuis (MAH) is an opportunistic pathogen that is ubiquitous in the environment and often isolated from faucets and showerheads. MAH mostly infects humans with an underlying disease, such as chronic pulmonary disorder (COPD), cystic fibrosis (CF), or are immunocompromised, though infections in patients without concurrent disease are...
Resource Type:: Masters Thesis
Full Text:: Chair of the Department of Microbiology Dean of the Graduate School I

The effects of X-ray CT scanning on microbial communities in sediment cores

Creator:: Ewton, Erica
Abstract:: Using X-ray computed tomography (CT) scanning to characterize the physical characteristics of soil and sediment cores allows scientists to observe and analyze stratigraphy without destroying the integrity of different layers. Microbiologists often work with geologists to characterize the microbial communities in such cores; however, X-rays are known to be destructive...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Toni Doolen, Dean, Oregon State University Honors College I understand

Identification of Autophagy Related Genes in Mycobacterium tuberculosis

Creator:: Miller, Carlin
Abstract:: A primary target of Mycobacterium tuberculosis is the human alveolar macrophage. Infection by this bacterium can lead to a variety of responses, such as apoptosis, autophagy, and necrosis, which may be involved in controlling the infection. M. tuberculosis has evolved mechanisms to evade or use the host-mediated processes to its...
Resource Type:: Honors College Thesis
Full Text:: your team for a few short months, and mentoring me through the writing process. I enjoyed the

Regulation of exopolysaccharide synthesis

Creator:: Dierksen, Karen P.
Abstract:: Lactococcus lactis subsp. cremoris Ropy 352 and L. lactis subsp. cremoris Hollandicus produce an exopolysaccharide (EPS) that imparts commercially desirable textural and rheological properties to fermented milk products. This ropy phenotype is expressed under specific environmental conditions. A mucoid EPS phenotype, also expressed under specific environmental conditions, but not involved...
Resource Type:: Dissertation
Full Text:: Microbiology Department of icrobiology Dean of Gradate School I understand that my dissertation will become

Regulating polysaccharide synthesis in bacteria

Creator:: Chen, Donald D.
Resource Type:: Masters Thesis
Full Text:: understanding of molecular and cellular biology, and I thank them for their efforts. I particularly thank Drs

The Genomic Capabilities of Microbial Communities Track Seasonal Variation in Arctic Lagoons

Creator:: Baker, Kristina D.
Abstract:: The lagoons spanning Alaska’s Beaufort Sea coast provide a unique habitat for arctic wildlife. These lagoons and the food webs they support face extreme seasonality with nine months of ice cover followed by a spring thaw that pulses a large amount of freshwater and nutrients into the lagoons. Bacteria link...
Resource Type:: Masters Thesis
Full Text:: the Department of Microbiology Dean of the Graduate School I understand

Characterization of germination of Clostridium perfringens spores from various sources

Creator:: Alnoman, Maryam M.
Abstract:: Clostridium perfringens is a pathogenic anaerobic bacterium able to produce more than 17 toxins, allowing C. perfringins to cause a wide variety of diseases in humans and animals. Beside toxins production, C. perfringens able to form a highly resistance spores can survive in the environments for years. These spores are...
Resource Type:: Masters Thesis
Full Text:: _____________________________________________________________________ Dean of the Graduate School I understand that my thesis will become a

Short lived bacterial regulatory proteins : what determines their fate?

Creator:: Ebel, Wolfgang, 1967-
Abstract:: Rapid degradation of certain short lived "timing" proteins is an effective mechanism for cells to control important regulatory pathways. The mechanisms by which regulatory proteases recognize their substrates are not well understood. Escherichia coli Lon, an energy dependent protease highly conserved in many prokaryotes and eukaryotes provides a model system...
Resource Type:: Dissertation
Full Text:: : Major Professor, representing/ Microbiology Department of Microbi Dean of duate School I understand

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