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Filtering by: Creator Garcia, Roberto Remove constraint Creator: Garcia, Roberto Degree Field Microbiology Remove constraint Degree Field: Microbiology

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  • Characterization of novel exopolysaccharide producing lactic acid bacteria

    Creator:
    Garcia, Roberto A., III
    Abstract:
    Lactic Acid Bacteria (LAB), an important group of organisms in modern food production, are known to secrete a unique compound called exopolysaccharide (EPS). EPS is economically important because it enhances functional properties in food and may confer beneficial health effects to consumers. Novel strains of Lactococcus lactis, Streptococcus thermophilus, and...
    Resource Type:
    Masters Thesis
    Full Text:
    AN ABSTRACT OF THE THESIS OF Roberto A. Garcia III

  • Harnessing Heterogeneity in Human Gut Microbiome Data

    Creator:
    Tataru, Christine
    Abstract:
    The focus of this thesis is to design, characterize, and apply novel computational methods and molecular systems to interrogate heterogeneous human gut microbiome-related phenomena. In Chapter 2, I design, implement, and characterize a method for embedding co-occurrence patterns derived from massive 16s amplicon datasets. I use this method to 1....
    Resource Type:
    Dissertation
    Full Text:
    interpretation, critical revision of the article Maya Livni, Elizaveta Zhivaya, Grace Deitzler, Manuel Garcia

  • The role of Salmonella typhimurium type three secretion system (T3SS) and effector proteins in chromatophore cell response.

    Creator:
    Farhad, Mohammad
    Abstract:
    Bacterial contamination of food poses a great risk to human health worldwide. A chromatophore cell-based biosensor, utilizing B. splendens erythrophore cells, is an emerging technology that has shown potential to detect bacterial toxicity based on function-dependent mechanisms. Previous studies have investigated the response of erythrophore cells to foodborne pathogens, pesticides,...
    Resource Type:
    Masters Thesis
    Full Text:
    graduate studies. I would like to thank all the Trempy lab members, especially Roberto Garcia and

  • A comparative study of fish coloration and toxicant responses in a chromatophore cell-based biosensor

    Creator:
    Roach, Holly B.
    Abstract:
    Detection of both biological and chemical environmental toxicants is essential in the assessment of risk to human health. Cell-based biosensors are capable of activity- based detection of toxicity. Chromatophore cells, responsible for the pigmentation of poikilothermic animal, have shown immense potential as cell-based biosensors in the detection of a broad...
    Resource Type:
    Masters Thesis
    Full Text:
    , Roberto Garcia, Dylan Ledford, Tyler Collins, Anthony Covington, Savannah Powell, and Sarah Michalski

  • Evaluation of peptide phosphorodiamidate morpholino oligomers as a novel antibiotic therapy

    Creator:
    Kaller, Margo
    Abstract:
    Peptide-phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA mimics that bind and silence gene targets. Through designing PPMOs that silence essential or resistance genes in pathogens, these antisense oligomers could be utilized as novel antimicrobials. Towards this end, my thesis employed minimum inhibitory concentration assays (MICs) to identify PPMOs capable of...
    Resource Type:
    Masters Thesis
    Full Text:
    Roberto Garcia III, Stephanie Rosales, and Wei Wei. Sharing so much laughter, commiseration, and tasty

  • Quorum sensing gene regulation in Pseudomonas aeruginosa

    Creator:
    Gupta, Rashmi
    Abstract:
    Pseudomonas aeruginosa is an opportunistic human pathogen that infects immunocompromised individuals such as those suffering from burns or the genetic disorder cystic fibrosis. This organism utilizes a cell-cell communication mechanism known as quorum sensing (QS) to coordinate virulence gene expression and biofilm formation. It has three interconnected QS systems, namely...
    Resource Type:
    Dissertation
    Full Text:
    ., 1997) activates expression of lasR (Albus et al., 1997) and rhlR (Croda-Garcia et al., 2011). At