Clostridium perfringens is the causative agent of gas gangrene and the 3rd most common cause of type A food borne disease in the United States. Critical to the pathogenicity of C. perfringens is the ability of this bacterium to produce highly resistant, metabolically dormant spores that can resume metabolic function...
The immune systems of various teleost fish have been studied in some detail for
the past several decades. One aspect of fish immunity, that of endogenously produced
modulating factors, has recently received a great deal of attention. Understanding the
functions and roles of endogenous factors that regulate fish immunity is...
Erythrocytic inclusion body syndrome (EIBS) was artificially
established in selected stocks of juvenile fall and spring chinook
salmon (Oncorhynchus tshawytscha), chum salmon (0. keta), coho
salmon (0. kisutch), Atlantic salmon (Salmo salar), and rainbow
trout (0. mykiss). Adult spring chinook salmon were also
artificially infected with the EIBS virus. Adult...
Utilization of zebrafish, Danio rerio, has steadily increased and its applications have expanded into numerous fields of science. Applying elevated temperatures (32°C to 37°C) to this organism has allowed researchers to conduct climate change, human cancer and infectious disease studies. Though zebrafish can be acclimated from the standard 28°C to...
The starvation-survival patterns of 16 freshly isolated open
ocean bacteria and in a psychrophilic Vibrio sp., Ant-300, were
determined. These isolates displayed three survival patterns as
determined by viable cell count. These were (a) a rapid increase
followed by a decrease to a constant value (pattern of Ant-300 and
7...
Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
The ability to move towards favorable environmental conditions, called chemotaxis, is common among motile bacteria. In particular aerotaxis has been extensively studied in Escherichia coli. Three putative aer gene homologs were identified in the V. cholerae genome designated VCAer-1 (VC0512) VCAer-2 (VCA0658), and VCAer-3 (VCA0988). Deletion analyses indicated that only...
Vibrio cholerae is the causative agent of cholera, a serious diarrheal disease in developing countries. V. cholerae has a unique redox driven respiration-linked sodium pump, Na⁺ translocating NADH:quinone oxidoreductase (NQR). Several reports previously showed that NQR plays an important role in virulence, metabolism, and sodium homeostasis of V. cholerae. This...
Disc gel electrophoresis of the vegatative cell -free extracts ofstrains of Clostridium botulinum types A, B, C, E, and F and therelated nontoxic group showed limited value as a means for identifyingthese closely related microorganisms, since separation,though not consistent in all cases, could only be based on the numberof protein...