Index Catalog // ScholarsArchive@OSU

In vitro and in vivo approaches for the functional characterization of the scaffold protein, GRASP

Creator:: Venkataraman, Anand
Abstract:: Studies using the pluripotent embryonic carcinoma cell line, P19, as a retinoic acid (RA)-responsive model system have been instrumental towards our understanding of the RA-dependent signaling pathways in development and homeostasis. Grp1-associated scaffold protein (GRASP; also known as Tamalin) was first identified by our group, as a gene robustly induced...
Resource Type:: Dissertation
Full Text:: regenerative medicine (8,9). A special class of these stem cells called embryonic carcinoma (EC) cells have

Functional Characterization and Classification of Genes Essential to Flower Induction, Flower Development, and Seed Development in Populus and Eucalyptus

Creator:: Elorriaga, Estefania
Abstract:: This dissertation consists of four studies of Populus and Eucalyptus biotechnology and genomic science: 1) induction of floral sterility by tapetal expression of the ribonuclease Barnase in Populus; 2) CRISPR Cas9-mediated gene editing targeting LEAFY (LFY) and AGAMOUS (AG) homologs in Populus; 3) induction of floral sterility by CRISPR Cas9...
Resource Type:: Dissertation

Comparative Metagenomic Investigations Link the Functional Capacity of the Gut Microbiome to Vertebrate Physiology

Creator:: Armour, Courtney R.
Abstract:: Microscopic organisms inhabit virtually every niche on this planet, where they perform functions vital to all life on earth. Accordingly, humans host a complex community of microorganisms (i.e. the gut microbiome) that inhabit the gastrointestinal tract and modulate host physiology. Insight into the specific mechanisms through which gut microbes influence...
Resource Type:: Dissertation

Pyoluteorin as a signaling molecule regulating secondary metabolite production and transport genes in Pseudomonas fluorescens Pf-5

Creator:: Brodhagen, Marion L.
Abstract:: A major factor in the ability of Pseudomonas fluorescens Pf-5 to act as a biological control agent is its production of antibiotics, including pyoluteorin (PLT), 2,4-diacetylphloroglucinol (2,4-DAPG) and pyrrolnitrin (PRN). The data provided in this thesis demonstrate that the presence of any of these antibiotics in the extracellular milieu affects...
Resource Type:: Dissertation

The proteomic and transcriptomic responses to iron, sulfur, and nitrogen limitation in the abundant marine bacterium Candidatus Pelagibacter ubique

Creator:: Smith, Daniel P.
Abstract:: Batch cultures of Candidatus Pelagibacter ubique were grown under iron-, organosulfur-, and nitrogen-limiting conditions to understand how this ubiquitous marine bacterium responds to and interacts with environments where growth is limited by the availability of these nutrients. Global gene expression was monitored using microarrays and quantitative mass spectrometry to observe...
Resource Type:: Dissertation

Interactions of auxin with ethylene and gravity in regulating growth and development in tomato (Lycopersicon esculentum, Mill.)

Creator:: Madlung, Andreas
Abstract:: Plant growth, development, and environmental responsiveness are dependent on hormone-induced gene expression. This dissertation reports multiple interactions between the plant hormones auxin and ethylene and investigates their contribution to the gravitropic response, elongation growth, adventitious root formation, callus and tracheary element initiation and growth, and flower development. Four mutants of...
Resource Type:: Dissertation

Regulation of phospholipase C-beta isozymes by calmodulin

Creator:: McCullar, Jennifer Star
Abstract:: Phospholipase C-Jβ (PLCβ) is an important effector enzyme in G-protein-coupled signaling pathways. Activation of PLCβ by Gα and Gβy subunits has been fairly well characterized, but little is known about other protein interactions that may also regulate PLCβ function. A yeast two-hybrid screen of a mouse brain cDNA library with...
Resource Type:: Dissertation

Proteomic analyses of marine bacteria

Creator:: Sowell, Sarah M.
Abstract:: Proteins are the metabolic machines of the cell and as such, the study of proteins could illuminate the dominant biological activities that are occurring within cells and reveal how an organism interacts with its environment. Here, we used proteomic techniques to study the abundant marine bacterium SAR11 both as an...
Resource Type:: Dissertation

From ALS to Antibodies: New Techniques in Mass Spectrometry-Based Proteoform Characterization

Creator:: Meeuwsen, Joseph C.
Abstract:: Altogether, this dissertation highlights the value of mass spectrometry-based analysis of intact proteins for solving problems related to understanding disease mechanisms and developing new therapeutics. Mutations to the antioxidant enzyme Cu, Zn Superoxide Dismutase (SOD1) perturb protein structure in vivo to cause 2-5% of amyotrophic lateral sclerosis (ALS) cases. Metal-deficient...
Resource Type:: Dissertation

ScholarsArchive@OSU

In vitro and in vivo approaches for the functional characterization of the scaffold protein, GRASP

Functional Characterization and Classification of Genes Essential to Flower Induction, Flower Development, and Seed Development in Populus and Eucalyptus

Comparative Metagenomic Investigations Link the Functional Capacity of the Gut Microbiome to Vertebrate Physiology

Pyoluteorin as a signaling molecule regulating secondary metabolite production and transport genes in Pseudomonas fluorescens Pf-5

The proteomic and transcriptomic responses to iron, sulfur, and nitrogen limitation in the abundant marine bacterium Candidatus Pelagibacter ubique

Interactions of auxin with ethylene and gravity in regulating growth and development in tomato (Lycopersicon esculentum, Mill.)

Regulation of phospholipase C-beta isozymes by calmodulin

Proteomic analyses of marine bacteria

From ALS to Antibodies: New Techniques in Mass Spectrometry-Based Proteoform Characterization

Limit your search

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search