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Filtering by: Advisor Dolan, Brian Degree Field Molecular and Cellular Biology

Non-Canonical Nedd8 Conjugation Mediated Targeted Protein Degradation and Direct Antigen Presentation

Creator:

Vijayasimha, Kartikeya

Abstract:

While the role of ubiquitin in protein degradation is well established, the role of other ubiquitin-like proteins (UBLs) in protein degradation is less clear. Neural precursor cell expressed developmentally down-regulated protein 8 (NEDD8) is the UBL with the highest level of amino acid identity when compared to ubiquitin. Here we...

Resource Type:

Dissertation

Full Text:

Presentation. Abstract approved: ______________________________________________________ Brian P. Dolan