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Filtering by: Committee Member Bermudez, Luiz Remove constraint Committee Member: Bermudez, Luiz Degree Field Molecular and Cellular Biology Remove constraint Degree Field: Molecular and Cellular Biology

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  • Vaccinia virus I7L core protein proteinase

    Creator:
    Byrd, Chelsea M.
    Abstract:
    Vaccinia virus (VV) is a large double-stranded DNA virus that is a prototypic member of the orthopoxvirus family. Previous works has showed that three of the major structural proteins found within the mature VV virion core 4a, 4b, and 25K are produced from higher molecular weight precursors at late times...
    Resource Type:
    Dissertation
    Full Text:
    committee members, Dan Arp, Dan Rockey, Walt Ream, and Luiz Bermudez for constructive criticism, freedom

  • Understanding chlamydial biology through genome sequencing and comparative genomics

    Creator:
    Jeffrey, Brendan
    Abstract:
    The human pathogen Chlamydia trachomatis displays different phenotypes between serovars both in vivo and in vitro. The study of chlamydial biology has been hampered by the lack of a tractable genetic system. Here, chlamydial isolates with known phenotypes as well as strains generated though recombination were fully sequenced to address...
    Resource Type:
    Dissertation

  • Molecular characterization of an HIV-1 drug target and antiviral compound development

    Creator:
    Maselko, Maciej
    Abstract:
    The Human Immunodeficiency Virus -1 (HIV-1) has been the source of substantial human misery since it was first discovered in the early 1980s. Despite remarkable progress that has been made towards understanding HIV- 1, there is no cure, no vaccine and life-prolonging therapies are beyond the reach of millions in...
    Resource Type:
    Dissertation