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Filtering by: Subject Chromatin Remove constraint Subject: Chromatin Degree Field Molecular and Cellular Biology Remove constraint Degree Field: Molecular and Cellular Biology

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  • Binding and assembly of H5 (and the globular domain of H5) onto DNA

    Creator:
    Carter, George John
    Abstract:
    In order to better characterize linker histone interactions with DNA, avian erythrocyte-specific linker H5 and the trypsin-resistant globular domain of H5 (GH5) were used in DNA binding studies. To begin, H5 displayed a considerably higher binding affinity for DNA than the isolated globular domain (GH5), supporting the importance of the...
    Resource Type:
    Dissertation
    Full Text:
    sedimentation studies indicate that H5 in itself was not sufficient to fully compact chromatin fibers; rather