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Filtering by: Creator Rodrigues, Amanda Degree Field Pharmaceutical Sciences Degree Level Doctoral

Development and implementation of a transkingdom network analysis pipeline to identify drivers of disease

Creator:

Newman, Nolan K.

Abstract:

The gut microbiome has been previously implemented in a number of diseases. Of note is its substantial role in metabolic syndrome, which encapsulates a group of conditions that increase the risk of cardiovascular disease, type 2 diabetes, and stroke. Understanding the causal relationships between the gut microbiome and host processes...

Resource Type:

Dissertation

Full Text:

Rodrigues and Amanda Bruce helped prepare the simulated data. Dr. Richard Rodrigues prepared the
Safety of Phytoestrogenic Botanical Dietary Supplements: in vivo and in vitro Evaluation of Botanical-Drug Interactions

Creator:

Chen, Luying

Abstract:

Popular botanical dietary supplements marketed for management of menopausal symptoms, including hops (Humulus lupulus L.), red clover (Trifolium pratense) and licorice (Glycyrrhiza uralensis), were evaluated for their potential to alter CYP-mediated drug metabolism clinically and pre-clinically. Both hops and red clover had been reported to inhibit certain cytochrome P450 (CYP)...

Resource Type:

Dissertation

Full Text:

Tonsing- Carter and Dr. Amanda Lee. I would like to thank Dr. Caitlin Howell from UIC for her sincere