Index Catalog // ScholarsArchive@OSU

Creator:: Doddapaneni, Bhuvana S.
Abstract:: Poor aqueous solubility of a large number of newly discovered chemical entities is posing a significant challenge for the formulation industry and is delaying their drug development. The number of formulation techniques available to solubilize these poorly soluble molecules is very limited. In addition to that, traditional formulation methods involve...
Resource Type:: Dissertation
Full Text:: my committee members Dr Oleh Taratula, Dr Mark Christensen, Dr Arup Indra and Dr Julie Greenwood

Creator:: Tse, Sunny
Abstract:: This dissertation presents a research series demonstrating the use of pharmacokinetic modeling and simulations as tools to assess drug concentration and disposition in patient populations. For drugs requiring therapeutic drug monitoring, these tools are necessary to ensure patients are receiving a safe and effective dose of medication to address their...
Resource Type:: Dissertation
Full Text:: . Rueda 5 , Ihab M. Wahba 6 1 Department of Pharmaceutical Sciences, Oregon State University

Creator:: Fan, Ying
Abstract:: This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
Resource Type:: Dissertation
Full Text:: encouragement and financial support. I also would like to thank my committee members, Dr. J. Mark Christensen

Creator:: Le, Uyen Minh
Abstract:: Cancer is one of the leading causes of death in the U.S., and new approaches to control cancer are constantly sought. This dissertation is comprised of two parts: (i) improving the uptake and retention of gadolinium in tumors for potential gadoliniumneutron capture therapy (Gd-NCT) and (ii) integration of gemcitabine or...
Resource Type:: Dissertation
Full Text:: financial support. I would like to thank Dr. J. Mark Christensen, Dr. Rosita Proteau, Dr. Lisa Madsen, and

Creator:: Alshahrani, Sultan M.
Abstract:: Foot pathology is a real problem in captive elephants. Osteoarthritis is the major concern among musculoskeletal disorders and foot health problems for elephants in North America zoos with one-‐half of Elephants in captivity showing foot health care problems in zoos. A higher ratio of captive Asian elephants (Elephas maximus) is...
Resource Type:: Dissertation
Full Text:: OF THE DISSERTATION OF Sultan M. Alshahrani for the degree of Doctor

ScholarsArchive@OSU