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Filtering by: Advisor Doerge, Robert Degree Field Pharmacy

The synthesis and preliminary pharmacological screening of some benzoyl diamides of ethylenediamine and piperazine

Creator:

Lindgren, Richard Eugene

Abstract:

Twelve N, N'-bis(hydroxy- and methoxybenzoyl)ethylenedi-amines and piperazines have been prepared, tested for antifungal activity, and screened for gross pharmacological activity in mice. All twelve compounds showed some activity against Candida albicans, Trichophyton mentagrophytes and Microsporum gypseum but in every case the activity was less than that of salicylanilide used as...

Resource Type:

Masters Thesis

Full Text:

and Experimental Therapeutics 108:450 -460. 1953. 37, Wyss, Orville, Bernard J. Ludwig and Robert R