Index Catalog // ScholarsArchive@OSU

The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

Creator:: Hardardt, Elizabeth Ann
Abstract:: This work sought to characterize a link between Vitamin C and nitroglycerin at the level of enzymatic bioactivation. Before we could proceed, we needed to develop a method that sensitively and selectively identified the product of bioactivation, nitrite. We successfully adapted traditional diaminonaphthalene derivatization with the use of stable isotope...
Resource Type:: Masters Thesis

Preparation and properties of Bentone ointment bases

Creator:: Billups, Norman Fredrick
Abstract:: A study has been made of ointment bases prepared from mineral oil thickened with Bentone 38 gellant. The experimental work was divided into two distinct parts: (1) the development of ointment bases using the Bentone gellants, and (2) subsequent comparison of these bases with White Petrolatum, Plastibase Hydrophilic, and other...
Resource Type:: Dissertation
Full Text:: absorb or emul- sify significant amounts of water led to the j-nvestigation of other hydrophilic

Gene networks during cardiogenesis and skeletal myogenesis

Creator:: Ma, Hsiao-Yen
Abstract:: Organismal development requires a precisely orchestrated transcriptional program to correctly deploy genetic information into the genome. This process requires sophisticated gene regulatory networks at multiple spatial and temporal levels from early embryonic development to adult physiological conditions. Molecular differences that define cell types are set up during the pattern formation...
Resource Type:: Dissertation
Full Text:: -721. Cai, C.L., Liang, X., Shi, Y., Chu, P.H., Pfaff, S.L., Chen, J., and Evans, S. (2003). Isl1

Development and broad application of a mass spectrometry based metabolomics platform

Creator:: Kirkwood, Jay Steven
Abstract:: Metabolomics is a comprehensive analysis of small molecules, or metabolites, in a system. Metabolomics is a hypothesis-generating experiment and offers an unbiased analysis of cell metabolism that can aid in the understanding of fundamental biological processes. Metabolomics is widely and broadly applicable in the biological sciences and has been used...
Resource Type:: Dissertation

Site-specific labeling of the cardiac glycoside receptor Na⁺,K⁺-ATPase : synthesis of a C-17 side group photoaffinity label ; Relationship of cardioactive steroid structure and conformation to biological activity

Creator:: Deffo, Tamboue Esaie
Abstract:: In an effort to isolate and characterize cardiac glycosides C-17 binding site(s), we have synthesized different affinity and photoaffinity C-17 side chain probes. These probes were screened for their ability to inhibit Na⁺,K⁺-ATPase enzyme, a pharmacological receptor of cardiac glycosides. The enzyme was isolated from hog kidney. Screening of these...
Resource Type:: Dissertation
Full Text:: introduced in the labeling of the digitalis receptor by B. Rossi et al. 13 More will be discussed on their

Studies on cardiotonic steroids and their receptor Na⁺,K⁺-ATPase

Creator:: Rathore, Hargovind S.
Resource Type:: Dissertation

Activation of adenosine receptors in prepiriform cortex modulates seizure susceptibility

Creator:: Zhang, Ge, 1956-
Resource Type:: Dissertation

Novel oxylipins and heterocycles from the Rhodophyta and Cyanophyta

Creator:: Jiang, Zhi-dong
Resource Type:: Dissertation
Full Text:: . George H. Constantine for his encouragement and cheerful times, Dr. Steven J. Gould for many good

Novel oxylipins and other bioactive metabolites from marine algae

Creator:: Nagle, Dale George
Abstract:: I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
Resource Type:: Dissertation
Full Text:: support: Dr. Philip J. Proteau, a great travel partner and friend, his commitment family, friends and to

Prevalance [sic] of senile dementia of the Alzheimer type (SDAT) in females receiving postmenopausal conjugated estrogen vs. controls : a retrospective review

Creator:: Gooch, Michael D.
Abstract:: Recent in vitro data provide evidence that estrogen may assist in the maintenance of nervous tissue viability. Anecdotal reports suggest a lower prevalence of SDAT in postmenopausal women who have received estrogen replacement therapy although published data are conflicting. The purposes of this study are to determine whether the incidence...
Resource Type:: Masters Thesis

ScholarsArchive@OSU

The effect of ascorbate on enzymatic nitroglycerin bioactivation as measured by direct LC-MS/MS determination of nitrite

Preparation and properties of Bentone ointment bases

Gene networks during cardiogenesis and skeletal myogenesis

Development and broad application of a mass spectrometry based metabolomics platform

Site-specific labeling of the cardiac glycoside receptor Na⁺,K⁺-ATPase : synthesis of a C-17 side group photoaffinity label ; Relationship of cardioactive steroid structure and conformation to biological activity

Studies on cardiotonic steroids and their receptor Na⁺,K⁺-ATPase

Activation of adenosine receptors in prepiriform cortex modulates seizure susceptibility

Novel oxylipins and heterocycles from the Rhodophyta and Cyanophyta

Novel oxylipins and other bioactive metabolites from marine algae

Prevalance [sic] of senile dementia of the Alzheimer type (SDAT) in females receiving postmenopausal conjugated estrogen vs. controls : a retrospective review

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