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Filtering by: Creator Reimers, Clare E. Degree Field Physics License Attribution 4.0 (CC BY 4.0)

Simulating the Dynein Motor Protein: A Monte Carlo Approach to Achieve Coordinated Stepping

Creator:

Kiatvongcharoen, Jin

Abstract:

The motor protein dynein is responsible for cellular processes such as axonal transport and cell division by delivering vital information along the microtubule track. A failed delivery can cause severe damage to the cell’s functionality and lead to neurological diseases. Despite dynein’s rich history in cellular research, the mechanism of...

Resource Type:

Undergraduate Thesis

Full Text:

and calculate the relative unbinding probability with a proportionality expression. That is, Pub ∝ e
Drunken Walking: A Novel Brownian Dynamics Simulation for the Mechanochemical Cycle of the Dynein Motor Protein

Creator:

Waczak, John L.

Abstract:

The dynein molecule is a peculiar motor protein recognized for its unique stepping behavior. Sometimes it steps forwards. Other times it steps backwards. It has even been observed to occasionally shuffle by beginning a step with the same domain many times in row. These motions make dynein an interesting object...

Resource Type:

Undergraduate Thesis