Index Catalog // ScholarsArchive@OSU

Chlordecone impaired biliary excretion : in vivo and in vitro correlates

Creator:: Rochelle, Lori G.
Resource Type:: Dissertation
Full Text:: Corvallis, Oregon 97331-3803 12 Abstract The effect of in vitro chlordecone (CD) treatment on hepatic

Developmental axial skeletal deformities : baseline study with a zebrafish model

Creator:: Harden, Jon M.
Abstract:: The aim of this study was to assess sensitivity of early life stage zebrafish to cadmium (Cd). Embryos and larva were exposed to Cd before the formation of skeletal elements. Exposure times were selected to determine whether Cd perturbed developmental processes that lead to skeletal deformities, and to characterize the...
Resource Type:: Masters Thesis
Full Text:: . There was no effect of Cd on incidence of any type of skeletal deformity at 4Odpf(P>O.05 and p>O.O5

Absorption and metabolism of selenite by perfused small intestine, and hepatocytes from rats

Creator:: Park, Yeong-Chul
Resource Type:: Dissertation
Full Text:: selenite on its absorption 25 Time course of sodium selenite transport 26 Chemical forms in the vascular

Oxidative stress and carcinogenesis in trout

Creator:: Kelly, Jack D.
Resource Type:: Dissertation
Full Text:: approved:4 David E. Williams The inhibitory effect of antioxidants in the multi-stage chemical

Vitellogenesis : a biomarker for estrogenic and antiestrogenic effects of organochlorines in rainbow trout

Creator:: Donohoe, Regina M.
Abstract:: Persistent organochlorines (OCs) bioaccumulate in aquatic biota and potentially impair reproduction via endocrine disruption. The present research evaluated estrogenic effects of the OCs, chlordecone (CD) and o,p'-DDT/DDE, and the antiestrogenicity of 3,4,5,3',4',5'-hexachlorobiphenyl (345-HCB) in juvenile rainbow trout, utilizing vitellogenesis as a biomarker. Vitellogenesis, estrogen regulated hepatic production of the yolk...
Resource Type:: Dissertation
Full Text:: synthesis and lipid metabolism (Cyr et al., 1988) but no evidence of a direct effect on Vg synthesis is

Congener-specific disposition of polychlorinated biphenyls in rainbow trout

Creator:: Foster, Eugene P.
Resource Type:: Dissertation
Full Text:: fish (Zabel et al., 1995). Interactions of compounds with minimal effect on metabolizing enzyme

Effects of chlorinated aliphatic hydrocarbon degradation on the metabolic enzymes in Nitrosomonas europaea

Creator:: Fawcett, Kimberly A.
Abstract:: The toxic effects of degrading the chlorinated hydrocarbons trichloroethylene (TCE), chloroform (CF) and cis-1,2-dichloroethylene (cis-1,2-DCE) were studied in the bacterium Nitrosomonas europaea. N europaea is an ammonia-oxidizing bacterium that obtains all of its energy from the oxidation of ammonia to nitrite. This metabolic process involves two enzymes, ammonia monooxygenase (AMO)...
Resource Type:: Masters Thesis
Full Text:: polypeptide and in vitro HA() activity 30 2. The effect of light and H202 on N} and N2H4 dependent 02

Sex and life stage sensitivity of rainbow trout to xenoestrogens

Creator:: Carlson, David B., 1970-
Abstract:: Numerous natural and anthropogenic chemicals interact with endocrine systems of animals. The most widely studied of these endocrine active chemicals (EACs) are estrogen receptor agonists and antagonists. Because of the many important roles of estrogens in animals, xenoestrogens have the potential to impact environmental health. It has been proposed that...
Resource Type:: Dissertation
Full Text:: exposure to aryl hydrocarbon receptor (AbR) agonists based on the sum of chemical affinity for AhR

Alteration of cholesterol disposition by chlordecone is not explained by induction of cyp7a or cyp4a1

Creator:: Lee, JungA
Abstract:: Liver X receptor (LXR), farnesoid X receptor (FXR) and peroxisome proliferator-activated receptor (PPAR) are adopted orphan nuclear receptors that function as lipid sensors. These receptors respond to cellular lipid levels and regulate the expression of target gene. Previously, it was demonstrated that low doses of chlordecone (CD) pretreatment disturbed exogenous...
Resource Type:: Masters Thesis
Full Text:: ). There was no significant effect of CD treatment on liver-to-body weight ratio calculated as liver

Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by dibenzo[a,l]pyrene in the B6 129 mouse model : role of the Aryl Hydrocarbon Receptor

Creator:: Yu, Zhen
Abstract:: Lymphomas and leukemias are the most common cancer in children and young adults and in utero exposure to carcinogens may contribute to the etiology of these cancers. A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l]pyrene (DBP), was administered to pregnant mice (15 mg/Kg b.w., gavage) on gestation day 17. Significant mortalities in...
Resource Type:: Dissertation
Full Text:: 3-2 Effect of AHR genotype on mortality of offspring born to DBP-treated dams

Effect of xenoestrogen exposure on the expression of cytochrome P450 isoforms in rainbow trout liver

Creator:: Intharapanith, Sirinmas
Resource Type:: Masters Thesis
Full Text:: metabolites formed by liver microsomes from each treatment 50 23. Effect of chemical treatments on plasma

Alterations in mink reproductive physiology following exposure to coplanar and noncoplanar polychlorinated biphenyls (PCBs)

Creator:: Patnode, Kathleen A., 1959-
Abstract:: Female mink (Mustela vison) are highly sensitive to polychlorinated biphenyl (PCB)-induced reproductive impairment. The goal of this research was to develop a better understanding of the mechanism of PCB-induced effects on female mink, mink embryos, and surviving mink kits. Anestrous, juvenile female mink and pregnant, adult mink were exposed to...
Resource Type:: Dissertation
Full Text:: Kathleen A. Patnode for the degree of Doctor of Philosophy in Toxicology presented on May 4, 1995. Title

Bioaccumulation of dietary 2,2',4,4',5,5'-hexachlorobiphenyl and induction of hepatic aryl hydrocarbon hydroxylase in rainbow trout (oncorhynchus mykiss)

Creator:: da Costa, Emmanuel G.
Resource Type:: Masters Thesis
Full Text:: presented on July 20, 1994 Title: Bioaccumulation of Dietary 2,2',4,4',5,5'-Hexachlorobiphenyl and

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Creator:: Bravo, Claudia F.
Abstract:: During the past 30 years, numerous studies have focused on the toxicities of polycyclic aromatic hydrocarbons (PAH). Laboratory and field studies have helped elucidate the detrimental effects of these chemicals on growth, reproduction and immune response. Polycyclic aromatic hydrocarbons are in the priority list of chemicals to be studied by...
Resource Type:: Dissertation
Full Text:: degree of Doctor of Philosophy in Toxicology presented on December 9. 2005. Title: Assessing Mechanisms

Environmental estrogens and skeletal development disruption in the fathead minnow : A teleost model of vertebrate developmental toxicity

Creator:: Warner, Kara E.
Abstract:: Natural and synthetic estrogenic compounds detected in surface waters have been linked to endocrine signaling disruption in several species. Endogenous estrogen contributes to cartilage and bone deposition during development in vertebrates, and is susceptible to perturbation from xenoestrogens. The goals of this work were to develop a teleost model to...
Resource Type:: Dissertation

Semi-volatile organic compounds and developing organisms : accumulation in California mountain tadpoles in the field and fish embryo exposures in the laboratory

Creator:: Stanley, Kerri A.
Abstract:: The atmospheric transport and deposition of semi-volatile organic compounds (SOCs), including current and historic use pesticides, polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs), to mountain ecosystems may result in the exposure of tadpoles to these SOCs. This exposure has been implicated in amphibian population declines in California. Tadpoles encounter...
Resource Type:: Dissertation
Full Text:: responsible for most of the sediment sample preparation for chemical analysis for Chapter 3. Dr. Robert

Size and surface area dependent toxicity of silver nanoparticles in zebrafish embryos (Danio rerio)

Creator:: Tuttle, George R.
Abstract:: Many studies addressing the toxicity of silver nanomaterials have found that smaller sized silver nanoparticles are usually more toxic to organisms and in cell culture than particles of larger sizes yet it is not entirely clear why. We investigated the size dependent toxicity of silver nanoparticles by measuring the response...
Resource Type:: Masters Thesis
Full Text:: 3.3 Effect of the Chorion on Embryo Toxicity……………………………………………………... 21 TABLE

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Creator:: Norby, Tyler S.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
Resource Type:: Masters Thesis
Full Text:: previous research, there was no significant (P > 0.05) effect on body weight of the fish in any of the

Environmental contaminants in male river otters collected from Oregon and Washington, 1994-99, with reproductive organ hypoplasia observed in otter males

Creator:: Grove, Robert Allan
Abstract:: A large number of river otter (Lontra canadensis) males were collected from areas of high and low contaminant concentrations throughout western Oregon and Washington during the fall and winter of 1994-99. Few significant non-reproductive organ morphometric differences were found in the large series of male otters collected, except for adrenal...
Resource Type:: Dissertation
Full Text:: degree of Doctor of Philosophy in Toxicology presented on May 25, 2006. Title: Environmental Contaminants

Environmental contaminants in male river otters collected from Oregon and Washington, 1994-99, with reproductive organ hypoplasia observed in otter males

Creator:: Grove, Robert Allan
Abstract:: A large number of river otter (Lontra canadensis) males were collected from areas of high and low contaminant concentrations throughout western Oregon and Washington during the fall and winter of 1994-99. Few significant non-reproductive organ morphometric differences were found in the large series of male otters collected, except for adrenal...
Resource Type:: Dissertation
Full Text:: Page 39 Three dimensional graph showing the predicted effects of increasing 'PCB concentrations on

ScholarsArchive@OSU

Chlordecone impaired biliary excretion : in vivo and in vitro correlates

Developmental axial skeletal deformities : baseline study with a zebrafish model

Absorption and metabolism of selenite by perfused small intestine, and hepatocytes from rats

Oxidative stress and carcinogenesis in trout

Vitellogenesis : a biomarker for estrogenic and antiestrogenic effects of organochlorines in rainbow trout

Congener-specific disposition of polychlorinated biphenyls in rainbow trout

Effects of chlorinated aliphatic hydrocarbon degradation on the metabolic enzymes in Nitrosomonas europaea

Sex and life stage sensitivity of rainbow trout to xenoestrogens

Alteration of cholesterol disposition by chlordecone is not explained by induction of cyp7a or cyp4a1

Indole-3-carbinol in the maternal diet provides chemoprotection for the fetus against transplacental carcinogenesis by dibenzo[a,l]pyrene in the B6 129 mouse model : role of the Aryl Hydrocarbon Receptor

Effect of xenoestrogen exposure on the expression of cytochrome P450 isoforms in rainbow trout liver

Alterations in mink reproductive physiology following exposure to coplanar and noncoplanar polychlorinated biphenyls (PCBs)

Bioaccumulation of dietary 2,2',4,4',5,5'-hexachlorobiphenyl and induction of hepatic aryl hydrocarbon hydroxylase in rainbow trout (oncorhynchus mykiss)

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Environmental estrogens and skeletal development disruption in the fathead minnow : A teleost model of vertebrate developmental toxicity

Semi-volatile organic compounds and developing organisms : accumulation in California mountain tadpoles in the field and fish embryo exposures in the laboratory

Size and surface area dependent toxicity of silver nanoparticles in zebrafish embryos (Danio rerio)

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Environmental contaminants in male river otters collected from Oregon and Washington, 1994-99, with reproductive organ hypoplasia observed in otter males

Environmental contaminants in male river otters collected from Oregon and Washington, 1994-99, with reproductive organ hypoplasia observed in otter males

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