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Filtering by: Committee Member Christopher, William Degree Field Toxicology

The progression of aflatoxin B₁ (AFB₁) hepatocarcinogenesis in rainbow trout (Oncorhynchus mykiss) : I. AFB₁ metabolism and cytotoxicity affecting hepatocarcinogenesis II. Ultrastructure of hepatocellular neoplasms

Creator:

Núñez, Oliva

Resource Type:

Masters Thesis
Involvement of inflammation and associated Mac-1⁺Gr-1⁺ cells in the immune suppression induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)

Creator:

Choi, Jin-Young, 1964

Abstract:

Exposure to TCDD suppresses the generation of immune responses through unknown mechanisms. Interestingly, TCDD enhances inflammatory responses to various stimuli. The goal of the studies presented in this thesis was to examine the role of hyperinflammation in TCDD-induced immunotoxicity. Previously we observed an increase in Mac-1⁺ cells in the spleen...

Resource Type:

Dissertation

Full Text:

thank to my committee members: Dr. Christopher Bayne, Dr. Jerry Heidel, Dr David Williams, Dr. Olaf