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Creator:: Jacobs, Dakota
Abstract:: Ovulation requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from preoptic hypothalamic neurons, initiated by elevated ovarian estradiol (E₂). Rising estradiol activates a subset of sexually dimorphic kisspeptin (Kiss-1) neurons in the female, located in the anteroventral periventricular nuclei (AVPV). Conversely, estradiol negative feedback on GnRH secretion is mediated by a...
Resource Type:: Masters Thesis
Full Text:: , we explored the impact of an endocrine disrupting class of perfluorinated alkyl substances (PFASs

Creator:: Haggard, Derik
Abstract:: There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...
Resource Type:: Dissertation
Full Text:: endocrine disrupting chemicals that can be used to classify the activity of known and unknown chemicals

Creator:: Grove, Robert Allan
Abstract:: A large number of river otter (Lontra canadensis) males were collected from areas of high and low contaminant concentrations throughout western Oregon and Washington during the fall and winter of 1994-99. Few significant non-reproductive organ morphometric differences were found in the large series of male otters collected, except for adrenal...
Resource Type:: Dissertation
Full Text:: system (endocrine). Some cells can even respond to their own chemical signals (cytocrine). A hormone is

Creator:: Grove, Robert Allan
Abstract:: A large number of river otter (Lontra canadensis) males were collected from areas of high and low contaminant concentrations throughout western Oregon and Washington during the fall and winter of 1994-99. Few significant non-reproductive organ morphometric differences were found in the large series of male otters collected, except for adrenal...
Resource Type:: Dissertation
Full Text:: . However, several of these contaminants are known endocrine-disrupting 3 chemicals which may be

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