Circadian regulation is essential for many physiological functions, from sleep/wake patterns to hormonal rhythms. While the brain’s biological clock, the suprachiasmatic nucleus (SCN), likely plays a role in reproductive rhythms, it remains unknown if intracellular circadian clocks elsewhere contribute to the neuroendocrine control of reproduction. Gonadotropin-releasing hormone (GnRH) stimulates pituitary...
If P is an integer polynomial denote the degree of P by ∂(P) and let H(P) be the maximum of the absolute value of the coefficients of P. Define Λ(P)=2[superscript ∂(P)]H(P) and for a fixed prime p let C[subscript p] denote the completion of the algebraic closure of the p-adic...
The remodeling of the central nervous system (CNS) during metamorphosis in Drosophila melanogaster is a prime model system in which to study the genetic control of the sexual dimorphisms in the abdominal ganglion of the CNS. I have been using a P[tau-lacZ] enhancer trap line, 4.078, to label a segmentally...
A sucrose density-gradient ultracentrifugation technique for
obtaining microsomes has been developed. This technique has
advantages over the classic differential centrifugation technique, in
that it is faster, is better suited to work with small quantities of
tissue, and offers the opportunity to work with a defined microsomal
sub-cellular fraction, rather than...
Many diseases cause a heavier burden on women than on men; however, treatment guidelines are based largely on data on men (NCBI, 2012). It becomes obvious that certain differences in genetics between men and women account for specific sex-related diseases, but there is too spare research focus on that issue....
This capstone project is expected to be published by United States Department of Agriculture Animal and Plant Health Inspection Service Wildlife Services (USDA APHIS WS) as part of a technical series guide available to the public through the website (https://www.aphis.usda.gov/aphis/ourfocus/wildlifedamage/sa_reports/ct_wildlife+damage+management+technical+series). USDA APHIS WS is responsible for mitigating human-wildlife conflict and...
Courtship and copulation behaviors in Drosophila melanogaster males are regulated by sex-specific products from the gene fruitless (fru). Male-specific FRU proteins (FRU[superscript M]) are putative transcription factors of the BTB-ZnF family that likely act by controlling development and maintenance of the neural circuitry used during male sexual behavior. However, which...