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Filtering by: Creator Howell, J. Franklin Remove constraint Creator: Howell, J. Franklin Degree Level Bachelor's Remove constraint Degree Level: Bachelor's File Format application/msword Remove constraint File Format: application/msword

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  • Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

    Creator:
    O'Donnell, Edmond Francis
    Abstract:
    DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
    Resource Type:
    Honors College Thesis

  • Investigating the Role of the MutLα Endonuclease

    Creator:
    Mankaney, Gautam Naresh
    Abstract:
    Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
    Resource Type:
    Honors College Thesis

  • Militant and nonviolent social movements

    Creator:
    Robinson, Blake
    Abstract:
    While much has been written about why people join social movements in general, little has been written about why people specifically join either militant or nonviolent social movements. Using the Black Panther Party as an example of a militant social movement and the mainstream Civil Rights Movement as an example...
    Resource Type:
    Honors College Thesis
    Full Text:
    Blake Robinson AN ABSTRACT OF THE THESIS OF Blake J