The detection of biomolecules is critical for clinical diagnostics but requires specialty labor and high cost. The use of microfluidic paper-based analytical devices (µPADs) for bioassays is simpler and cheaper but has low sensitivity. Improved immobilization of antibodies onto cellulose is demonstrated through surface functionalization with APTES and glutaraldehyde. The...
Tooth decay in the form of dental caries and cavities is estimated to be among the most common health conditions globally, with treatment of these oral diseases resulting in a massive, world-wide economic burden. The cause of this demineralization of teeth is rooted in the action of complex microbial biofilms...
The development of simple, rapid, and sensitive methods for thiophenol detection is of great importance in various fields, including environmental monitoring and food quality. Here, we present a novel approach for the colorimetric detection of thiophenols using gold nanoparticles (AuNPs) as the sensing platform. AuNPs aggregate in the presence of...
The ability of nanoparticles (NPs) to induce oxidative stress on organisms has been linked to NP cytotoxicity and genotoxicity for a variety of organisms. One proposed mechanism of this increased oxidative stress is the ability of NPs to generate reactive oxygen species (ROS). Due to the dynamic nature and small...
The discovery of new blue pigments is a field of great interest, as commercially available pigments present properties that make them undesirable such as poor sustainability, cost, and stability. By researching solid solutions with the melilite structure, we discovered a new solid solution Sr2Zn1-xNixGe2O7, with 0.1 ≤ x ≤ 0.6,...
The anticonvulsant drug carbamazepine (CBZ) is a commonly prescribed drug that is used to treat patients with neurological disorders including epilepsy and bi-polar disorder. CBZ has a narrow range of efficacy: Below the therapeutic dose, seizures and other conditions are not controlled, and above the recommended window, patients experience side...
Water splitting is a green method being researched to produce green hydrogen in order to combat greenhouse gases emitted by the most popular energy source; fossil fuels. Water splitting involves two half reactions: hydrogen evolution reaction (HER) and oxygen evolution reaction (OER). Of these two, OER is the bottleneck water...
Sepsis is a blood infection caused by circulating pathogens and cell wall fragments that affects over 1 million patients per year in the United States. When bacterial cell membranes are lysed by antibiotics, cell wall fragments containing lipopolysaccharides (LPS) are released. As a result, the capture of LPS is critical...
Nanoparticles (NPs) are generally defined as particles <100 nanometers (nm) in size in one dimension. Despite increasing industrial usage of TiO2 NPs in sunscreens, cosmetics, and water remediation little is known of their environmental behavior. The primary goal of this research was to develop a rapid method for determining the...