Chlamydia trachomatis is an obligate intracellular pathogen that affects millions of people worldwide via ocular or reproductive tract infection. Despite obvious differences in site of infection, there has been shown to be high levels of sequence conservation across C. trachomatis. This high level of sequence conservation is hindered with a...
Chlamydia possesses an immense importance within both human and animal medicine when looking at pathogens. Chlamydia trachomatis infections have been shown to affect both the eye and genital tracts in millions of humans and animals every year [13]. As C. trachomatis strains are highly conserved in patients, it has made...
Our laboratory is exploring the mechanism of action of a novel broad spectrum antiviral, ST-669. This compound has activity against a variety of different viruses and the obligate intracellular bacterium, Chlamydia. In this study, we explored the effects of ST-669 when the cell cycle of the host cells was altered....
Our laboratory group is studying the molecular target of a novel, broad-spectrum antiviral compound known as ST-669. This compound has activity against a variety of different viruses and also obligate intracellular bacteria in the genera Coxiella and Chlamydia. The goal of this thesis project was to help elucidate the mechanism...
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Daniel Rockey
Our laboratory group is studying the molecular target of a novel, broad
The extensive adoption of social media has provoked widespread debate about how
online communication impacts social relationships. An apparent paradox of Facebook
is that people simultaneously express feeling more and less connected than ever
before. Through perspectives from psychology and communication studies, this thesis
addresses a question of public concern:...
Studying the evolution of the Milky Way galaxy helps us understand our place in the Universe. Early evolution of the Galaxy can effectively be studied by observing stars with low metallicity values since they are the oldest stars still visible. Due to the formation of the Galaxy, the oldest stars...
Pantoea agglomerans pathovar betae (Pab) is a bacterium that causes galls on the roots of beet plants, resulting in reduced marketability of beet roots and crop loss. Pab uses a type III secretion system (T3SS) to infect and cause galls on beets. The T3SS is a molecular syringe-like structure that...
Respiratory illnesses caused by both viral and bacterial infection are serious issues for global healthcare providers. With the emergence of new, drug-resistant forms of these diseases, innovative drugs and treatment therapies are needed. M tuberculosis is an infection that affects a large portion of the world’s population each year. Aerosol...
Chlamydia trachomatis is an obligate intracellular bacterium that causes diseases of the eye and urogenital tract in humans. It is the cause of the sexual transmitted infection (STI) chlamydia, the most prevalent STI worldwide, and the ocular disease trachoma, the leading cause of infectious blindness. To date there is no...