Monitoring phenylalanine (Phe) levels in the blood of individuals with phenylketonuria (PKU) is a critical component of therapy. Existing tests for PKU require high-resource laboratories, which are not available to many populations and cannot provide the real-time feedback required for effective therapy monitoring. It would be ideal to develop an...
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Dr. Elain Fu
Abstract
Monitoring phenylalanine (Phe) levels in the blood of individuals
Prostate cancer is the most common cancer among men in the United States. There are an estimated 115,024 incident cases so far in 2017. Risk factors for prostate cancer include age, black race, and family history of prostate cancer. In addition, healthful diet and lifestyle may affect risk of prostate...
Electrochemical sensing provides a quantitative alternative to colorimetric reactions within paper-based devices. The paper-based devices were fabricated by screen printing the conductive and reference inks onto porous substrates that were evaluated using cyclic voltammetry. Devices were evaluated based on the magnitude of the average anodic peak height, which correlates with...
Diatoms are single celled eukaryotic microalgae that self-assemble complex SiO₂
nanostructures by sillafin proteins within their cell wall. There has been increasing
interest in mimicking the diatom’s silica self-assembly process for fabricating metal
oxide nanoparticles, namely germanium dioxide (GeO₂). GeO₂ has a higher refractive
index than silica, enabling it to...
The development of simple, rapid, and sensitive methods for thiophenol detection is of great importance in various fields, including environmental monitoring and food quality. Here, we present a novel approach for the colorimetric detection of thiophenols using gold nanoparticles (AuNPs) as the sensing platform. AuNPs aggregate in the presence of...
The majority of people suffer from back pain at some point in their lives. Back pain is the leading cause of disability globally, ahead of 290 other conditions1. Over one million people in the United States receive spine surgery annually2. This thesis looked at five standard surgical procedures performed on...
Users curate music playlists based on emotion to focus or relax, so streaming services often create playlists of songs to aid this process. Prior research focuses on generating playlists of a single mood or genre, although a few studies work to construct automatic playlists that transition between the genres of...
The topic of this paper is the Anti-Chinese Movement which happened in the 19th century in the United States. On the one hand, this paper explores and proves that although numbers of Chinese immigrants were described as passive victims in the movement by American contemporary press and scholars, the Chinese...
Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
The WWC family consists of three proteins‐ KIBRA/WWC1, WWC2, and WWC3. The three proteins share a similar primary structure and interact with a common set of proteins. Each paralog contains two WW domains which recognize proline‐rich sequences of the type PPxY (P is proline, Y is tyrosine, x is any...