Although Latino students make up more than a quarter of the U.S. public school system, only three percent of children’s literature either features a Latino protagonist or is written by a Latino author (Machado et al.). Latinos are therefore severely underrepresented in children’s books. Additionally, studies have revealed that Latino...
Evaporation synergy is a phenomenon that occurs between different classes of soil and allows for a greater amount/quantity of soil water evaporation. 20 of the 66 soil texture class combinations have been shown to exhibit evaporation synergy (Fisher, 2012), however the impact of column width on the functionality of this...
Although computer science (CS) education researchers and practitioners have found ways to improve CS classroom inclusivity, few researchers have considered inclusivity of online CS education. We have begun developing a new approach that we term “embedded inclusive design” to address inclusive CS. The essence of the approach is to integrate...
Knowledge of the pore solution composition and pore solution resistivity can be helpful for determining the durability of concrete structures. Most notably, pore solution resistivity can be used in the calculation of the formation factor of concrete, which is a ratio of the electrical resistivities of concrete and its pore...
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O. Burkan Isgor, Committee Member, representing Civil and Construction Engineering
RNA silencing plays a critical role in plant defense against viral infection. Plants use virusderived
small interfering RNA to target and silence invading viruses. The antiviral silencing
pathway can be broken down into three conceptual stages: initiation, amplification, and systemic
movement. The molecular mechanisms of silencing initiation are not well...
Oil is notorious for its volatility. Often as an indicator for economic wellbeing, the commodity employs millions across the country. Entire communities in the western United States are centered around oil extraction, with employment, livelihoods, and revenues dependent on oil’s success. This combination of factors begs the question, how do...
Neurofibromatosis type 2 (NF2) is a genetic disorder caused by the inactivation of the
merlin tumor suppressor gene. NF2 patients develop bilateral vestibular schwannomas
(VS) and other nervous system tumors with no effective drug treatment option. In
pathological conditions, including NF2, production of the oxidant peroxynitrite leads to
protein tyrosine...
Neurofibromatosis Type 2 (NF2) is a genetic tumor disorder caused by mutations that inactivate the gene coding for the Merlin tumor suppressor. Patients with NF2 develop multiple tumors throughout the nervous system, mainly schwannomas, for which there is no cure or effective treatment. In NF2, redox signaling and oxidative stress...
This work is concerned with determining whether nicotine has a role in promoting oxidative damage in human tissue, particularly in lung tissue. This follows from recent reports of a novel lung disease found in some E-cigarette users, characterized by oxidative damage and elevated levels of neutrophils (termed “vaping disease”). It...
Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in the motor cortex and spinal cord. Recent evidence suggests that the purine receptor P2X7 (P2X7R) plays a central role in the pathology of ALS. Previous research indicates that P2X7R activation by oxidatively modified heat shock protein 90...
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Maria Franco, Committee Member, representing Biochemistry and Biophysics Department